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MoonDragon's Obgyn Information
ANOVULATION
(Ovarian Infertility)


"For Informational Use Only"
For more detailed information contact your health care provider
about options that may be available for your specific situation.




DESCRIPTION

Anovulation is a cycle in which a woman does not ovulate, or does not release an egg(s). Some women have many, or all, cycles in which they do not ovulate. Most of the time there is no menstrual bleeding, or if there is bleeding, it is because of the low estrogen and is called breakthrough bleeding. Many times a woman will see this bleeding and assume that she is ovulating.

There can be many reasons why a woman does not ovulate. And most of the time, a health care provider can prescribe drugs that will bring on ovulation. A woman who does have some bleeding once a month would never know she was anovulatory unless she was charting her basal body temperatures. A chart would look very erratic - with the temperature jumping all over the place - with no upward shift to identify ovulation.





CAUSES

  • Breastfeeding.

  • Pre-menopause (perimenopause) and menopause.

  • Hormone therapy: such as, coming off oral contraceptives pill or other hormones such as Depo-Provera. Hormone imbalances are the most probable cause of anovulatory cycle. The long-term use of certain medications. Steroidal oral contraceptives (the Pill) are sometimes responsible. These drugs work by intentionally disrupting the hypothalamic-pituitary-ovarian axis, suppressing ovulation and thereby preventing pregnancy. For women using long-acting injectable steroid contraceptives (Depo-Provera), it appears likely that the longer the contraceptive is continued the more likely it is that amenorrhea will result.

  • Polycystic ovarian syndrome.

  • Illnesses. Illnesses such as hypothalamic dysfunction, hyperprolactinemia, luteal phase defects, or tumors of the pituitary gland adrenal gland or ovaries. Other causes of anovulatory cycles are primary ovarian failure, resistant ovary syndrome and autoimmune oophoritis.

  • Stress and anxiety. Anxiety and other forms of emotional stress can also take their toll on normal ovulation.

  • Travel.

  • Strenuous exercise. A prolonged strenuous program of exercise, such as running, can interfere with the ovulatory cycle by suppressing the output of hormones called gonadotropins from the hypothalamus in the brain.

  • Excessive weight gain or loss. Eating disorders interfere with the ovulation cycle.

  • Medical conditions such as pituitary gland problems and polycystic ovarian disease can cause a woman to stop ovulating altogether.

    MoonDragon's Obgyn Information: Amenorrhea, Secondary

    MoonDragon's Obgyn Information: Polycystic Ovary

    MoonDragon's Obgyn Information: Stress

    MoonDragon's Health Information: Underweight

    MoonDragon's Obgyn Information: Obesity

    MoonDragon's Obgyn Information: Bulimia

    MoonDragon's Pediatric Information: Anorexia Nervosa

    MoonDragon's Obgyn Contraception Information: Contraception Index

    MoonDragon's Obgyn Information: Female Infertility

    Once you know the probable causes of anovulation, you must take care to avoid any of these, especially if you have a history of fertility problems. Avoid any strenuous exercise without consultation and do not attempt to try out fad diets as these may lead to anovulatory cycles. Learn to manage stress and develop a healthy lifestyle to keep this disorder at bay.





    TREATMENT


    Anovulation can be difficult to detect. Some women have seemingly normal menstrual periods even though they are not ovulating. Most often, women who do not ovulate also do not menstruate, a disorder known as amenorrhea, or do not menstruate regularly, a condition called oligomenorrhea. Because of this, scant, erratic, short and/or painless menstrual cycles can sometimes alert a woman or her doctor about an anovulation problem.

    If you experience bleeding between periods for more than 2-3 cycles, you should notify your health care provider immediately. Too many of these anovulatory cycles can contribute to irregular bleeding, or endometrial hyperplasia. A diagnostic test for anovulatory cycles may include the following depending on other factors like your age and medical history. TESTS
    • Serum assays.
    • LH (on days 13 and 15 of menstrual cycle, to detect midcycle peak).
    • FSH.
    • Progesterone.
    • Prolactin.
    • DHEA-SO4.
    • Testosterone and SHBG (for obtaining Free Androgen Index [FAI] or calculated free testosterone levels)
    • CT scan or MRI scan of pituitary and hypothalamus.
    • Endometrial biopsy.
    • Ovarian biopsy.
    • Specific antibody tests.

    TREATMENT FOR ANOVULATORY CYCLES

    Treatments for anovulatory cycles vary based on the underlying cause of the condition and other factors like age and medical history. For many infertile women with anovulation, treatment with one or another of fertility drugs can be remarkably successful. Clomiphene citrate (Clomid) is often a good first choice for an anovulatory woman who is producing estrogen.

    If clomiphene alone is unsuccessful, Pergonal is added to bolster the attempts to ripen a follicle. Pergonal bypasses the natural hormone stimulation of the pituitary on the ovary. It applies stimulation directly to the ovary, and then, once a follicle grows to sufficient size, HCG is used as the final step to release the egg.

    Some other treatments that can used in tandem with medication are :
    • Medications for specific underlying conditions.
    • Nutritional modifications.
    • Stress reduction.
    • Surgery (in the case of tumors).




    MEDICATION

  • If you are trying to conceive, anovulation can be frustrating. Treatment is possible, if you choose to remedy the situation. If you suspect anovulation, you need to contact your health care provider for a series of tests to check hormone levels. Usually fertility drugs are prescribed which bring on ovulation. The most widely prescribed drugs are Clomid or Pergonal. These are usually prescribed in small doses to give the body a chance to ovulate, and then the dosage is gradually increased until ovulation occurs. Some women will ovulate only with the help of these drugs. Of the two, Clomid is the least invasive and is usually prescribed when the root of infertility cannot be determined.

  • If there is no menstrual bleeding, a drug called Provera, or a similar drug, is given to induce menstruation. Once ovulation has been established your health care provider can better determine if additional treatment is needed.

    Women are happy that in this day and age anovulation is not a reason for infertility. With the advances in technology, medicine, and the deeper understanding of natural alternative therapies there are choices available that can be utilized to help nature along.

    Before trying any therapy, charting your fertility cycle is a necessity. Research your options and discuss them with your health care provider.





    HERBAL & HOLISTIC RECOMMENDATIONS

    There are several natural herbs that can help to bring on ovulation. You should check with your midwife, herbalist or health care provider before taking any supplement.

  • Vitex (Chast Berry) can help to regulate the hormones estrogen and progesterone and aids in ovulation (as well as many other menstrual problems). Check the bottle to see how much to take. This will depend upon the type of herbal supplement you decide on. Information is available below about Vitex and where to find it. It is not recommended to take Vitex in conjunction with Clomid.

  • A good dose of vitamin B6 - between 25-100 mg a day - can help to lengthen the luteal phase and will aid in fertility.

    PMS formula with B-6 Nature's Way PMS Formula with 5 HTP & Vitamin B-6, 100 caps

  • Evening Primrose Oil taken before the expected ovulation can aid in the production of egg-white cervical fluid, which is the most fertile fluid. Evening Primrose Oil is especially helpful in treating pre-menstrual syndrome (PMS), menstrual cycle irregularities, menopause, and endometriosis. It is used to promote smooth skin and to treat actopic eczema. It is also used in the treatment of arthritis, particularly rheumatoid arthritis, and to improve proper joint function. It is also useful in the treatment of diabetic neuropathy, Mastalgia (breast pain), prostatic hypertrophy, gastrointestinal disorders, viral infections, Alzheimer's, cardiovascular disease, and hypertension. Evening primrose oil may interfere with certain medications. It is best to consult with your health care provider or midwife before use. Safety in young children, pregnant or nursing women, or those with severe liver or kidney disease is not known.
    Amenorrhea & Anovulation Supplements

    Information and supplements for help with amenorrhea & anovulation, the absence of menstrual periods and/or the ovarian infertility.

    Evening Primrose Oil, NOW Foods 100% Pure - 4 fl. oz.

    Evening Primrose Oil is rich in Gamma Linolenic Acid (GLA). Each 1 ml of oil contains 80-100 mg of GLA. Evening primrose oil has been cold pressed at a low temperature to obtain a pure, natural, and virgin oil.
    Evening Primrose Oil, Cold Pressed, Nature's Way 1300mg - 120 Softgels

    Nature's Way EFA Gold is the highest quality Evening Primrose Oil - guaranteed to contain 10% gamma-linolenic acid (GLA).
    Evening Primrose Oil, Cold Pressed, Nature's Way 500mg - 250 Softgels

    Nature's Way EFA Gold is the highest quality Evening Primrose Oil - guaranteed to contain 10% gamma-linolenic acid (GLA).
    Evening Primrose Oil By Nancy L. Morse

    This Book explains how Evening Primrose works in the body to both prevent ailments and maintain health.
    Blue Cohosh (Caulophyllum thalictroides) Tincture, 100% Organic - 2 fl. oz.

    Blue Cohosh is used to regulate the menstrual flow and for treating suppressed menstruation.
    Female Estrogen with Progestrone Tincture, 100% Organic - 2 fl. oz.

    Female Estrogen With Progestrone formula is used mainly to promote hormonal balance. It does not contain hormones, however.
    Vitex Fruit (Chaste tree), 400mg - 100 Caps

    Vitex is a woman's dietary supplement, traditionally used for menstrual difficulties. Vitex has been heavily researched in Europe. It is widely used to promote overall health and balance in a woman's life.
    Chaste Tree Berry / Vitex Tincture, Fertility and Herbal PMS Remedy - 2 fl. oz.

    Chaste Tree Berry is an Herbal PMS remedy and a natural fertility herb. Trials have shown genuine effectiveness of Chaste Tree Berries for women suffering from infertility and irregular periods.
    Relora, NOW Foods 300mg - 60 Caps

    Relora is used to normalize hormone levels associated with stress-induced obesity and poor eating and drinking behaviors. Preliminary findings suggest that Relora can decrease the cravings for high fat and high sugar foods in stressed individuals.
    PROGESTA, Natural Progesterone Cream - 2 oz.

    Progesta is a unique natural progesterone supplement that provides incredible feminine support for overall mental health, normal feminine cycles and more.
    Motherwort Tincture, 100% Organic - 2 fl. oz.

    Research has shown that Motherwort is able to calm palpitations and irregular heartbeat.
    Yarrow Flowers, 325mg - 100 Caps

    Yarrow (achillea millefolium) may be helpful for Nosebleeds, fevers, colds, sore throat, indigestion, heartburn, inflammation, menstruation, dysmenorrhoea, high blood pressure, muscle spasms, urinary tract infections, and minor injuries.
    False Unicorn Tincture, 100% Organic - 2 fl. oz.

    Many herbalists recommend False Unicorn for reducing menopausal symptoms, and treating ovarian cysts. It has also been used to normalize hormone levels following oral contraceptive use.
    DIM-Plus Estrogen Metabolism / Diindolylmethant Protectamins Cruciferous Nature's Way - 120 Caps

    DIM-Plus Estrogen Metabolism Formula promotes healthy estrogen metabolism, Relieves PMS symptoms, Promotes fat loss, supports breast, cervical, uterine and prostate health. Scientific research shows diindolylmethane increases the level of "good" estrogens (2-hydroxyestrogen) while reducing the level of "bad" estrogens (16-hydroxyestrogen).
    Super Lignan - Herbal Estrogen Supplement - Nature's Way, 60 Vcaps

    EFAGold (TM) Super Lignan is an ideal herbal estrogen supplement for supporting breast health during the menopausal phases of life helping alleviate breast tenderness and pain associated with the menstrual cycle.
    Calcium Complex Bone Formula Nature's Way - 100 Caps

    Calcium, Magnesium, and other minerals help maintain normal structure and development of bones. Studies have shown that calcium supplementation may help to maintain normal bone density among women as they age.
    Appetite Stimulant Formula Tincture, 100% Organic - 2 fl. oz.

    This herbal appetite stimulant has been designed by a Master Herbalist to stimulate the appetite. It combines herbs well known, and recommended by the German Commission E, for improving the appetite and eliminating symptoms of appetite loss.
    Tansy Herb Tincture, 100% Organic - 2 fl. oz.

    Tansy Herb Tincture is used to expel worms, especially round and thread worms.
    Woman's Raspberry Leaf, Female Support - 16 Tea Bags

    Our Organic Woman's Raspberry Leaf is a gentle and organic way to support the special needs of a woman's reproductive system.
    Natural Progesterone Cream: A Safe Alternative to Conventional Hormone Replacement Therapy, By C. Norman Shealy, M.D., Ph.D.

    In this Keat's Good Health Guide, Dr. Norman Shealy answers all your questions about natural progesterone cream, a viable and safe alternative to synthetic hormone replacement therapy.


    PRODUCTS FOR CYCLE CHARTING, OVULATION MONITORING, PREGNANCY TESTS













    NOTIFY YOUR MIDWIFE OR HEALTH CARE PROVIDER IF


  • You or a family member has symptoms of anovulation and/or amenorrhea. If you are a woman and have missed more than one period so that the cause, and appropriate treatment, can be determined.

  • Periods don't begin in 6 months after treatment.

  • New, unexplained symptoms develop. Hormones used in treatment may produce side effects.




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