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MoonDragon's Health & Wellness
Nutrition Basics

Antioxidants
CURCUMIN

Turmeric (Curcumin Longa) Herbal Information


For Informational Use Only
For more detailed information contact your health care provider
about options that may be available for your specific situation.





  • Antioxidant Overview
  • Curcumin (Turmeric) Description
  • Curcumin (Turmeric) Uses, Health Benefits, & Scientific Evidence
  • Curcumin (Turmeric) Dosage Information
  • Curcumin (Turmeric) Safety, Cautions, & Interactions
  • Curcumin (Turmeric) Supplements & Products




  • ANTIOXIDANT OVERVIEW

    FIGHTING FREE RADICALS

    Antioxidants are vitamins, minerals, and other nutrients that protect and repair cells from damage caused by free radicals. Many experts believe this damage plays a part in a number of chronic diseases, including hardening of the arteries (atherosclerosis), cancer, and arthritis. Free radicals can also interfere with your immune system. So, fighting off damage with antioxidants helps keep your immune system strong, making you better able to ward off colds, flu, and other infections.

    Antioxidants are compounds that neutralize the cellular-damaging effects of free radicals. Free radicals are produced naturally in your body, but when you exercise hard, your body pumps out more free radicals. Environmental factors such as pollution, the sun, cigarette smoke, and herbicides can also spawn free radicals. The danger is that free-radical damage may lead to cancer. Antioxidants interact with and stabilize free radicals and may prevent some of the damage that free radicals otherwise might cause. As an active person, more antioxidants may help you slow the aging process, ward off cancer and stress, and promote good health.





    turmeric (curcumin) root and powder


    CURCUMIN (TURMERIC) DESCRIPTION

    AN ANTI-INFLAMMATORY SPICE

    Turmeric, also known as Curcumin and Curcuma longa, is part of the ginger family (Zingiberaceae) and is a popular spice widely cultivated throughout India, China and Indonesia. It is the major ingredient in curry, a spice that is used quite liberally in the Indian diet. Turmeric is useful as an anti-inflammatory, and has anti-cancer effects, but recent research studies have suggested that curry rich in Curcumin has the ability to reduce the effects of Alzheimer's. India has one of the lowest Alzheimer's disease rates in the world, estimated at one percent of individuals over 65, whereas, ten percent of Americans over 65 develop Alzheimer's disease.

    Curcumin is the principal curcuminoid in Turmeric. Turmeric's other two curcuminoids are desmethoxycurcumin and bis-desmethoxycurcumin. The curcuminoids are natural phenols that are responsible for the yellow color of Turmeric. Curcumin can exist in several tautomeric forms, including a 1,3-diketo form and two equivalent enol forms. The enol form is more energetically stable in the solid phase and in solution. Curcumin can be used for boron quantification in the curcumin method. It reacts with boric acid to form a red-colored compound, rosocyanine. Curcumin is brightly yellow colored and may be used as a food coloring. As a food additive, its E number is E100.

    TURMERIC - CURCUMIN ANTIOXIDANTS

    Curcumin can potentially benefit health by promoting the immune system, helping maintain a healthy digestive system, supporting healtlhy bones, joints and overall skeletal system, helping to maintain cholesterol levels that are already within normal range and promoting healthy blood and liver functions. Turmeric antioxidants help protect cells from free radical damage. The antioxidant content within Turmeric comes from the active curcuminoid compounds. These compounds deliver antioxidants that may be 5 to 8 times stronger than vitamin E and also stronger than vitamin C, 3 times more powerful than grape seed or pine bark extract and strong enough to scavenge the hydroxyl radical, considered by many to be the most reactive all all oxidants.

    The organic ingredients found in Turmeric can help promote healthy skin. Curcuminoids support important blood and liver functions, healthy joints and overall well-being, which in turn helps promote radiant, supple skin. Turmeric has been considered to be a skin food for thousands of years in India and other cultures. Turmeric helps cleanse the skin and maintain its elasticity, provide nourishment to the skin and balance the effects of skin flora. Turmeric can act against normal aging with its skin promotion and antioxidant capabilities resulting in outer beauty plus an inner purity.

    Turmeric can assist your cells in three ways by helping neutralize substances that can cause cellular stress, maintaining cell integrity when threatened by occasional environmental stressors, and providing the antioxidants needed to help support cells against excessive oxidation and free radicals. Turmeric is also recognized as an adaptogen, helping to support the body against stress and providing immune support.

    AYURVEDIC PRACTICE & TURMERIC

    Ayurveda is India's ancient holistic system meaning "knowledge of life" with herbs lying at the very heart of Ayurvedic practice. Turmeric, like other herbs and spices, is a principle herb in Ayurveda with multiple uses, including blood cleansing and maintaining healthy skin. In Ayurvedic terminology, Turmeric includes the following:
    • Verda sthapana: Promotes a healthy nervous system and helps with occasional discomfort.
    • Sangrahani: Supports absorption of vitamins and minerals.
    • Anulomana: Helps in purging out wastes and building healthy blood.
    • Rakta stambhaka: Promotes the wellness of the circulatory system.

    This is only a fraction of Ayurvedic uses. Turmeric has been used in Indian culture for thousands of years for a multitude of health-promoting reasons. An estimated 500 million Indian people still use the spice today.

    CURCUMIN CHEMISTRY

    Curcumin incorporates several functional groups. The aromatic ring systems, which are phenols, are connected by two alpha,beta-unsaturated carbonyl groups. The diketones form stable enols and are readily deprotonated to form enolates. The alpha,beta-unsaturated carbonyl grouup is a good Michael acceptor and undergoes nucleophilic addition. Western scientists first isolated the curcumin molecule in 1815 and obtained its crystalline form in 1870. The overall structure was first identified in 1910 by J. Mitobedzka, Stanislaw Kostanecki and Wiktor Lampe. Curcumin is used as an indicator for boron.





    TURMERIC-CURCUMIN USES, HEALTH BENEFITS, & SCIENTIFIC EVIDIENCE

    BENEFITS

    Turmeric is useful as an anti-inflammatory and can be used to reduce Alzheimer’s debilitating effects, but there are multiple studies that suggest Curcumin can have some potential in actually treating various forms of cancer by its ability to suppress tumor initiation, tumor promotion, and even metastasis (the spread of cancer). The studies suggest that Curcumin has enormous potential in the prevention and therapy of cancer. It has been shown to lessen the symptoms of Benign Prostatic Hyperplasia (BPH).

    Turmeric also appears to have a positive effect on gall bladder function and can aid in lowering cholesterol. The German Commission E approves Turmeric for a variety of digestive disorders such as gastritis, Curcumin is the active ingredient in Turmeric which induces the flow of bile and helps break down fats.

    Preliminary studies have shown this herb may also help relieve the symptoms of osteoarthritis, prevent the blockage of arteries (athersclerosis), and treat roundworms and intestinal worms. As a topical, it can help prevent bacterial infection in wounds.

    HEALTH RESEARCH

    Although some preclinical studies suggest Curcumin may be useful for the prevention and treatment of several diseases, the effectiveness of Curcumin has neither been confirmed in sufficient preliminary research, nor has it been demonstrated in randomized, placebo-controlled, double-blind clinical trials.

    In one preliminary study, a daily dose of 2 grams of Curcumin extract was found to provide pain relief that was equivalent to ibuprofen for the relief of pain associated with osteoarthritis of the knee. A survey of the literature shows a number of other potential uses and that daily doses over a 3 month period of up to 12 grams proved safe. Some commercial capsules of Curcumin contain piperine, a compound found in pepper which aids absorption of Curcumin into the blood stream.

    The effect of Curcumin on amyloid beta plaque build up, a possible major cause for Alzheimer’s, has been studied in mice. According to theory, Curcumin may provide anti-inflammatory effects in a neuro-inflammatory cascade in plaque pathogenesis. The study demonstrated that both low and high doses of Curcumin reduced beta-amyloid plaque buildup, an effect that may be similar to that of aspirin which suppressed development of beta-amyloid plaque buildup in preliminary research.

    Research in the latter half of the 20th century identified Curcumin as the agent responsible for most of the biological activity of turmeric. In vitro and animal studies have suggested potential biological effects associated with Curcumin. At present, these effects have not been confirmed in humans.

    As of 2008, clinical trials in humans were underway, studying the effect of Curcumin on various diseases, including multiple myeloma, pancreatic cancer, myelodysplastic syndromes, colon cancer, psoriasis, and Alzheimer's disease.

    Several preliminary research studies have identified Curcumin with potential biological effects:
    • In both in vitro and animal studies, Curcumin has shown antitumor, antioxidant, antiarthritic, antiamyloid, anti-ischemic, and anti-inflammatory properties.
    • Anti-inflammatory properties may be due to inhibition of eicosanoid biosynthesis.
    • In one study, Curcumin protected mice from V. vulnificus-induced septicemia.
    • A study found Curcumin hepatoprotective in combination with Absinthium in rats.
    • A laboratory study found that low concentrations of Curcumin interfere with Herpes simplex virus-1 (HSV-1) replication. It inhibited the recruitment of RNA polymerase II to viral DNA, thus inhibiting its transcription. This effect was independent of the effect on histone acetyltransferase activities of p300/CBP.
    • One study found that Curcumin may be associated with protection from infection by HSV-2 in animal models of intravaginal infections.
    • A study in rats found that Curcumin may act as a free radical scavenger and antioxidant, inhibiting lipid peroxidation and oxidative DNA damage, protecting against lead neurotoxicity.
    • In rats, Curcumin was shown to be effective in protecting against toxicity and spatial memory impairment induced by amyloid beta-protein infusion.
    • A study using a transgenic animal model indicated that Curcumin diminished plaque burden and overall inflammation, but it also increased plaque-associated inflammatory cells suggesting enhanced clearance.
    • A study found that Curcumin shrank the size of plaques and reduced neurite dystrophy in an Alzheimer mouse model.
    • A study found Curcumin to have a synergistic effect with fish oil to protect against cognitive deficits in a transgenic rodent model.
    • Preliminary studies indicate that Curcumin may have a positive effect on neurogenesis in the hippocampus and may increase levels of brain-derived neurotrophic factor (BDNF) in rats.
    • A Curcumin pyrazole derivative was found to improve memory and was neuroprotective, stimulating BDNF in vitro and in vivo. The compound was found to be protective in animal models of brain trauma and stroke.
    • In rats, Curcumin may inhibit cardiac hypertrophy and affect cardiac health and repair through different mechanisms.
    • In one preliminary human study, Curcumin increased insulin secretion from the pancreas.
    • A human study of 240 subjects observed that Curcumin could reduce the risk of having a type 2 diabetes.

    CANCER RESEARCH

    The potential anti-cancer effects of Curcumin have been the subject of several preliminary studies:
    • Curcumin's potential anticancer effects may stem from an ability to induce apoptosis in cancer cells without cytotoxic effects on healthy cells. Curcumin may interfere with activity of the transcription factor NF-KB, which has been linked to a number of inflammatory diseases such as cancer.
    • One study suggested Curcumin may inhibit a cancer-associated complex via mechanisms yet to be defined.
    • An in vitro study in a human glioblastoma cell line reported that Curcumin may inhibit tumor cell proliferation, migration and invasion, and that these effects may be mediated through interference with a signaling pathway.
    • When 0.2 percent Curcumin was added to the diet of rats or mice previously given a carcinogen, it reduced incidence of colon carcinogenesis.
    • In one in vitro study Curcumin had phyto-estrogenic activity that might affect onset of breast cancer.
    • In immunodeficient mice with breast cancer, Curcumin inhibited the formation of lung metastases, possibly through the regulation of cytokines.
    • A study found that Curcumin might affect kidney function by reducing lipopolysaccharide-induced renal inflammation.

    BIOAVAILABILITY

    In Phase I clinical trials, dietary Curcumin was shown to exhibit poor bioavailability (i.e., low levels in plasma and tissues). Potential factors that limit the bioavailability of curcumin include poor absorption, rapid metabolism, and rapid systemic elimination. Numerous approaches to increasing Curcumin bioavailability have been explored, including the use of adjuvants like piperine.

    The bioavailability of Curcumin ingested in foods may be increased as a result of cooking or dissolution in oil.

    RESISTANCE

    Overexpression of the ATP-binding cassette gene ABCA1 has been reported to confer resistance to Curcumin in terms of NFkappaB activation that can be reversed by ABCA1 silencing.


    Chemistry and Research Information obtained from Wikipedia: Curcumin. For a complete article and list of references, visit their web page.




    CURCUMIN-TURMERIC DOSAGE INFORMATION

    SUPPLEMENT FORMS

    Curcumin is the active ingredient of turmeric, and is also found in limited amounts in Ginger. It is a potent anti-inflammatory and cancer preventative molecule, and similar to Fish Oil it seems to be an effective metabolic syndrome band-aid. Black Pepper greatly enhances absorption.

    There are various forms of Turmeric. You can use it to season your food, or buy it in capsule or pill form to take as a supplement. It is important to follow product label directions before use.

    For any systemic purpose (requiring absorption from the intestines), then an oral supplementation of curcumin in the range of 80 to 500 mg would be required assuming an enhancement. Curcumin is poorly absorbed inherently, and one of the following is mandatory:
    • Pairing curcumin with Black Pepper (Piperine).
    • Curcumin phytosomes complexed with Phosphatidylcholine (Meriva or BCM-95).
    • Curcumin nanoparticles (Theracurcumin).
    • Water-soluble curcumin (Polyvinyl Pyrrolidone).

    If one of the above enhancements are not used, then too little curcumin will be absorbed and even doses of up to 4,000 mg may be wholly inactive (8 to 16 g would only be slightly active). If using curcumin for intestinal purposes, then absorption from the intestines into the blood is not necessarily required. Due to this, one can simply use Turmeric at the dose of 2 to 4 g daily or take curcumin supplementation without any of the aforementioned enhancements.

    CHOOSING SUPPLEMENTS

    Avoid supplements that contain unnecessary fillers, additives and excipients. An excipient is a substance added to the supplement as a processing or stability aid. One ingredient, magnesium stearate (known as stearic acid) is a potentially toxic metal additive from pill production. Dibasic Calcium Phosphate (DCP) may inhibit the absorption of essential minerals within your system. There are others, but the base line is - you do not want or need these ingredients in your turmeric supplement. Some can pose potential health risks and all are unnecessary.

    Make sure your herbal supplement comes from a reliable certified organic producer committed to quality processing and products. Look for supplements that contain only 100-percent certified organic ingredients and with Turmeric extract, at least 95-percent curcuminoids. Do not rely on low quality grocery store spice.

    Additionally, when the spice is heated during cooking many of the beneficial properties are lost. Look for supplements in a vegetable capsule and avoid gelatin-based capsules whenever possible. Do not settle for inferior products.

    A good merchant source is Turmeric-Curcumin Products below for recommendations.





    CURCUMIN-TURMERIC SAFETY, CAUTIONS, & INTERACTIONS

    SAFETY CONCERNS

    Turmeric is considered safe when taken in the recommended doses; however, taking excessive amounts may produce stomach upset and, in extreme cases, ulcers. NOTE: Normal therapeutic doses of Turmeric protect from ulcers, but at very high doses, it may induce ulcers. This is why it is very important to take only the recommended dose of this herbal remedy. Turmeric should not be taken by those who have been diagnosed with gallstones or obstruction of the bile passages without explicit direction from a qualified practitioner. Safety in young children, pregnant or nursing women, or those with severe liver or kidney disease is not known.

    CURCUMIN SAFETY RESEARCH

    Kawanishi et al. remarked that Curcumin, like many antioxidants, can be a "double-edged sword" where, in the test tube, carcinogenic and pro-oxidant effects may be seen in addition to anticancer and antioxidant effects. Carcinogenic effects are inferred from interference with the p53 tumor suppressor pathway, an important factor in human colon cancer. In vitro and in vivo studies suggest that Curcumin can have carcinogenic effects.

    Clinical studies in humans with high doses (2 to 12 grams) of Curcumin have shown few side effects, with some subjects reporting mild nausea or diarrhea. More recently, Curcumin was found to alter iron metabolism by chelating iron and suppressing the protein hepcidin, potentially causing iron deficiency in susceptible patients. Further studies seem to be necessary to establish the benefit/risk profile of curcumin.

    There is no or little evidence to suggest Curcumin is either safe or unsafe for pregnant women. However, there is still some concern medicinal use of products containing curcumin could stimulate the uterus, which may lead to a miscarriage, although there is not much evidence to support this claim. According to experiments done on rats and guinea pigs, there is no obvious effect (neither positive, nor negative) on the pregnancy rate or number of live or dead embryos. Curcumin has embryotoxic and teratogenic effects on zebrafishes (Danio rerio) embryos.


    RESEARCH RESOURCES

  • Kawanishi, S.; Oikawa, S.; Murata, M. (2005). Evaluation for safety of antioxidant chemopreventive agents. Antioxidants & Redox Signaling 7 (11–12): 1728–1739.
  • Moos, P. J.; Edes, K.; Mullally, J. E.; Fitzpatrick, F. A. (2004). Curcumin impairs tumor suppressor p53 function in colon cancer cells. Carcinogenesis 25 (9): 1611–1617.
  • Burgos-Moron, E.; Calderon-Montano, J. M.; Salvador, J.; Robles, A.; Lopez-Lazaro, M. (2010). The dark side of curcumin (pdf). International Journal of Cancer 126 (7): 1771–1775.
  • Dance-Barnes, S. T.; Kock, N. D.; Moore, J. E.; Lin, E. Y.; Mosley, L. J., et al. (2009). Lung tumor promotion by curcumin. Carcinogenesis 30 (6): 1016–1023.
  • Lopez-Lazaro, M.; Kock, N. D.; Moore, J. E.; Lin, E. Y.; Mosley, L. J., et al. (2008). Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent. Molecular Nutrition and Food Research 52 (Supplement 1): S103–S127.
  • Hsu, C. H.; Cheng, A. L. (2007). Clinical studies with curcumin. Advances in Experimental Medicine and Biology. Advances in Experimental Medicine & Biology 595: 471–480.
  • Jiao, Y.; Wilkinson, J.; Di, X.; Wang, W.; Hatcher, H., et al. (January 2009). Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood 113 (2): 462–469.
  • Vijayalaxmi (1980). Genetic effects of turmeric and curcumin in mice and rats. Mutation Research 79 (2): 125–132.
  • Wu, J. Y.; Lin, C. Y.; Lin, T. W.; Ken, C. F.; Wen, Y. D. (2007). Curcumin Affects Development of Zebrafish Embryo. Biol. Pharm. Bull 30 (7): 1336–1339.





  • TURMERIC / CURCUMIN SUPPLEMENTS & PRODUCTS

  • Turmeric-Curcumin Herbal Products


  • QUALITY SUPPLIES & PRODUCTS


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    TURMERIC (CURCUMIN) HERBAL PRODUCTS

    Turmeric is a traditional Indian cooking spice and the chief ingredient of Curry. Turmeric improves digestion and purifies the blood and is believed to act as a natural antibiotic and antiseptic. Curcumin, turmeric's active constituent, protects against free radical damage because it is a strong antioxidant. It is a powerful anti-inflammatory and protects against inflammatory calcium loss from our bones. It also reduces inflammation by lowering histamine levels and possibly by increasing production of natural cortisone by the adrenal glands. It protects the liver from a number of toxic compounds. It also has been shown to prevent platelets from clumping together, which in turn improves circulation and helps protect against atherosclerosis. There are also numerous animal studies showing a abnormal cell growth-preventing action of curcumin. This may be due to its antioxidant activity in the body. Turmeric also acts as a mild antacid.

    STARWEST BOTANICALS PRODUCTS

    Organic Turmeric Rhizome Sliced

    Starwest Botanicals: Turmeric Rhizome, Sliced, Organic, 1 lb.

    Organic Turmeric Root Powder

    Starwest Botanicals: Turmeric Root Powder, Organic, 1 lb.

    Organic Turmeric Powder Jar

    Starwest Botanicals: Turmeric Root Powder, Organic, 2.19 oz. Jar

    Turmeric Capsules

    Starwest Botanicals: Turmeric Root Capsules, 500 mg, 100 VCaps
    Starwest Botanicals: Turmeric Root Capsules, 500 mg, 500 VCaps



    HERBSPRO PRODUCTS

    HerbsPro: Turmeric, Woodland Publishing, 36 Page Booklet (90242)
    HerbsPro: Meriva Turmeric Complex, Source Naturals, 30 Tabs (89114)
    HerbsPro: Curcumin Extract, Now Foods, 60 VCaps (68032)
    HerbsPro: Black Cumin Seed Oil With Bio Curcumin, Life Extension, 60 Softgels (109053)
    Black Cumin Seed oil is particularly effective for a balanced immune and inflammatory response. Contains black cumin seed oil and BCM-95 Bio-Curcumin 25:1 extract standardized to 95% total curcuminoids complex with Turmeric essential oils.
    HerbsPro: Turmeric Root Extract, Standardized, Bluebonnet Nutrition, 60 VCaps (100920)
    HerbsPro: Turmeric Force, New Chapter, 60 Softgels (82320)
    HerbsPro: Turmeric Root Extract, Standardized, Solgar, 60 VCaps (36787)
    HerbsPro: Turmeric Standardized Extract, Natures Way, 60 Tabs (18109)
    HerbsPro: Meriva Turmeric Complex, Source Naturals, 60 Tabs (89115)
    HerbsPro: Turmeric, Oregon's Wild Harvest, 60 Caps (83562)
    HerbsPro: Turmeric & Ginger, Natures Answer, 90 LCaps (106996)
    HerbsPro: India Turmeric Formula, Organic, 90 VCaps (84064)
    HerbsPro: Turmeric Root (Curcuma Longa), Eclectic Institute, 90 Caps (67561)
    HerbsPro: Curcumin, Kyolic, 100 Caps (112595)
    HerbsPro: Turmeric, Kroeger Herb, 100 VCaps (88352)
    HerbsPro: Turmeric Root Extract, Standardized, Bluebonnet Nutrition, 120 VCaps (100921)
    HerbsPro: Meriva Turmeric Complex, Source Naturals, 120 Tabs (89116)
    HerbsPro: Curcumin BCM 95, Genceutic Naturals, 250 mg, 60 VCaps (88006)
    Curcumin is the active compound in turmeric, a bright yellow, ancient spice and a traditional remedy that has been used for health, as well as for condiment and flavoring purposes, based on records dating back to more than 2000 years. Turmeric has a long history of use in traditional Chinese and Ayurvedic systems of health. Genceutic Naturals Curcumin has 19 times the curcumin content of the ground turmeric spice. The herbal compound curcumin, may help to relieve common, everyday inflammation triggered by a host of lifestyle factors. This property is due, at least in part, to its mechanism of action as a natural COX-2 inhibitor (COX-2 is an inflammatory enzyme). Furthermore, curcumin has well-established properties as an antioxidant protector against free radicals. In fact, its antioxidant properties are as strong as vitamin C and vitamin E. Research suggests that these two important properties in curcumin may help support healthy immune function, healthy brain function, healthy cell growth and cell division, healthy liver function, and healthy cholesterol levels already within a normal range. May help to relieve common, everyday inflammation. Powerful antioxidant properties comparable to vitamins C and E. May support healthy immune, brain, cellular, liver and cardiovascular function Curcu-Gel BCM-95 curcumin has 8.2 times greater bioavailability.
    HerbsPro: Turmeric, Organic, Genceutic Naturals, 300 mg, 60 Caps (78068)
    HerbsPro: Turmeric Extract, Thompson Nutritional Products, 300 mg, 60 Caps (35714)
    HerbsPro: Curcuminrich Turmeric Root Extract Theracurmin, Natural Factors, 300 mg, 60 VCaps (106846)
    Curcumin is the yellow pigment of turmeric valued for its many health benefits. CurcuminRich Turmeric Root Extract with Theracurmin is an enhanced form that increases absorption over 30 times compared to regular curcumin.
    HerbsPro: Turmeric Extract, Standardized 95% Curcumin, Source Naturals, 350 mg, 50 Tabs (6689)
    Curcumin, considered the most bioactive and soothing portion of the herb tumeric, shows protective effects on the liver. It also inhibits the cox-II enzyme and is a powerful antioxidant. When taken alone, curcumin has very poor absorption. Bioperine greatly enhances the bioavailability of curcumin. Contains Turmeric Extract Yielding Curcumin 350 mg Plus 333 mg, Bromelain (extracted from pineapple) 50 mg, (2,000 G.D.U.)
    HerbsPro: Turmeric Extract, Standardized 95% Curcumin, Source Naturals, 350 mg, 100 Tabs (6690)
    Curcumin, considered the most bioactive and soothing portion of the herb tumeric, shows protective effects on the liver. It also inhibits the cox-II enzyme and is a powerful antioxidant. When taken alone, curcumin has very poor absorption. Bioperine greatly enhances the bioavailability of curcumin. Contains Turmeric Extract Yielding Curcumin 350 mg Plus 333 mg, Bromelain (extracted from pineapple) 50 mg, (2,000 G.D.U.)
    HerbsPro: Super Bio-Curcumin, Life Extension, 400 mg, 60 VCaps (91798)
    Curcumin is impressing scientists around the world with its remarkable multiple health benefits. Curcumin is a polyphenol present in the spice turmeric and was first used by Indians over 3,000 years ago in traditional Ayurvedic medicine. Modern science has found that curcumin has remarkable antioxidative, immunomodulatory, proapoptotic, hepatoprotective and antiangiogenic properties.Curcumin is also found to increase detoxifying enzymes and promote healthy DNA function. Studies have tied inflammation to overexpression of a protein molecule called nuclear factor-kappa B (NF-kappaB). NF-kappaB acts like a switch to turn on genes that produce the bodys inflammatory responses. Because NF-kappaBs expression increases in aging adults, scientists have sought ways to modulate NF-kappaB and its effects in the body. Curcumin has been shown to exert powerful inhibitory effects on NF-kappaB activation within the body. Curcumin inhibits overexpression of NF-kappaB. In addition, curcumin inhibits the metabolism of arachidonic acid, as well as activities of cyclooxygenase, lipoxygenase, and cytokines (interleukins and tumor necrosis factor). Other clinical trials suggest roles for curcumin in helping maintain healthy lipid profile, bowel, and joint functions.Curcumin can also help maintain normal healthy platelet function,and have immunomodulatory effects by inhibiting histamine release from mast cells.Other studies show curcumins potential for supporting healthy brain function and offering neuroprotection. Curcumin may effectively support pancreatic islet health.Curcumins multifaceted effects include protecting against estrogen-mimicking chemicals, protecting against damaging free radicals, and promoting normal cell cycle growth. The problem is that curcumin is poorly absorbed into the bloodstream. Super Bio-Curcumin absorbs up to seven times better than conventional curcumin. So this patented formula represents the most cost-effective way to supplement with this critical nutrient. Studies show that one 400 mg capsule a day of this turmeric compound can provide curcumin blood levels equal to ingesting 2,5002,800 mg of commercial curcumin supplements. And not only does this turmeric formulation provide far greater peak blood levels, but the curcumin remains in the bloodstream almost twice as long as conventional supplements. And this enhanced absorption delivery complex provides other beneficial turmeric compounds in addition to standardized curcumin. Each 400 mg capsule of Super Bio-Curcumin is equivalent to 2,772 mg of a typical 95% curcumin extract.
    HerbsPro: Full Spectrum Turmeric Extract, Planetary Herbals, 450 mg, 60 Tabs (6611)
    HerbsPro: Turmeric Standardized Extract, 95% Curcuminoids, Natures Way, 450 mg, 120 Tabs (62678)
    HerbsPro: Full Spectrum Turmeric Extract, Planetary Herbals, 450 mg, 120 Tabs (62740)
    HerbsPro: Turmeric Gold, Planetary Herbals, 500 mg, 30 Tabs (89015)
    HerbsPro: Turmeric Gold, Planetary Herbals, 500 mg, 30 Caps (89018)
    HerbsPro: Turmeric Gold, Planetary Herbals, 500 mg, 60 Tabs (89016)
    HerbsPro: Turmeric Gold, Planetary Herbals, 500 mg, 60 Caps (89019)
    HerbsPro: Curcumin-95, Antioxidant Protection, Jarrow Formulas, 500 mg, 60 Caps (1124)
    Curcumin 95 is a concentrate of 95% curcuminoids, which are powerful antioxidants found in the spice turmeric root. Specifically, curcumin and its derivatives protect DNA against oxidative damage induced by reactive oxygen species.
    HerbsPro: Bio-Curcumin Phytosome, Now Foods, 500 mg, 60 VCaps (85971)
    Curcumin, the active polyphenolic extract of Turmeric Root, is one of the best scientifically investigated plant compounds. However, Curcumin's health-supporting properties depend on limited oral absorption. Now Foods Bio-Curcumin Phytosome is a patented Curcumin complexed with phosphatidylcholine that clinically demonstrates increased absorption and bioavailability, as compared to standard Curcumin extracts. Clinical studies also show that bio-Curcumin Phytosome provides potent antioxidant activity, can support a balanced inflammatory response, and can promote healthy joint mobility and flexibility.
    HerbsPro: Turmeric Gold, Planetary Herbals, 500 mg, 120 Tabs (89017)
    HerbsPro: Turmeric Gold, Planetary Herbals, 500 mg, 120 Caps (89020)
    HerbsPro: Curcumin-95, Antioxidant Protection, Jarrow Formulas, 500 mg, 120 Caps (67579)
    Curcumin 95 is a concentrate of 95% curcuminoids, which are powerful antioxidants found in the spice turmeric root. Specifically, curcumin and its derivatives protect DNA against oxidative damage induced by reactive oxygen species.
    HerbsPro: Curcumin Phytosome Meriva, Doctors Best, 500 mg, 180 VCaps (109015)
    Curcumin nutrients (curcumin, demethoxycurcumin, bisdemethoxycurcumin) are usually poorly absorbed when taken by mouth. Phytosome proprietary technology solves this problem. In Curcumin Phytosome featuring Meriva , each curcuminoid molecule is individually complexed with molecules of the vital cell membrane nutrient phosphatidylcholine (PC). By facilitating curcumins entry into human cells and tissues, PC gives this product superior bioactivity over non-phytosome curcumin supplements.
    HerbsPro: Curcumin Extract 95%, Now Foods, 700 mg, 120 VCaps (71691)
    Used internally for Digestive Complaints. Curcumin is the major component of Turmeric (Curcuma longa L.) and extensive scientific research on Curcumin has demonstrated its potent antioxidant properties. Through its antioxidant mechanisms, Curcumin supports colon health, exerts neuroprotective activity and helps maintain a healthy cardiovascular system.
    HerbsPro: Turmeric Extract, Source Naturals, 1000 mg, 30 Tabs (83812)
    HerbsPro: Kyolic Curcumin With Bioperine, Healthy Inflammation Response, Wakunaga Kyolic, 1000 mg, 50 Caps
    Curcumin is the key antioxidant in the spice turmeric, long used for its powerful phenolic antioxidant benefits. BioPerine is a standardized form of piperine extract derived from black pepper. BioPerine increases the absorption of Curcumin by significantly increasing its bioavailability. Aged Garlic Extract [150 mg]; Curcumin Longa Extract (Curcumin C3 Complex) [500 mg]; Piperine Black Pepper Extract (BioPerine) [2 mg] (per capsule). Kyolic Curcumin is a synergistic combination of Curcumin C3 Complex, BioPerine and odorless, organic Aged Garlic Extract to provide nutritional support for healthy inflammation response. Kyolic is made by a special extraction process to maximize beneficial compounds and is supported by many published studies across a wide range of health benefits. Take Kyolic Curcumin each day to provide a powerful and natural support for healthy inflammation response, joint function, cardiovascular benefit, colon and liver health, as well as a variety of other nutritional benefits.
    HerbsPro: Turmeric Extract, Source Naturals, 1000 mg, 60 Tabs (83813)
    HerbsPro: Turmeric Extract, Source Naturals, 1000 mg, 120 Tabs (83814)
    HerbsPro: Best Curcumin C3 Complex with Bioperine, Doctors Best, 1000 mg, 120 Tabs (76393)
    HerbsPro: Turmeric Extract, Herb Pharm, 1 fl. oz. (31347)
    HerbsPro: Turmeric Extract, Herb Pharm, 4 fl. oz. (32349)
    HerbsPro: Turmeric Extract, Full Spectrum, Planetary Herbals, 1 fl. oz. (83764)
    HerbsPro: Turmeric Extract, Full Spectrum, Planetary Herbals, 2 fl. oz. (83765)
    HerbsPro: Turmeric Extract, Full Spectrum, Planetary Herbals, 4 fl. oz. (83766)


    KALYX PRODUCTS

    Kalyx: Turmeric Extract, Thompson Nutrition, 300 mg, 60 Caps: K
    Kalyx: Turmeric Root, Certified Organic, Starwest Botanicals, 550 mg, 100 VCaps: C
    Kalyx: Turmeric Root, Certified Organic, Starwest Botanicals, 550 mg, 500 VCaps: C
    Kalyx: Turmeric Root Powder (Curcuma longa; Yu Jin), Vadik Herbs, 100 VCaps: B

    Ground Powdered

    Kalyx: Turmeric Root Powder, Certified Organic (Curcuma longa; Yu Jin), Simply Organic, 0.53 oz: K
    Kalyx: Turmeric Root Powder, Certified Organic, Fair Trade Certified (Curcuma longa; Yu Jin), Frontier Herbs, 1.41 oz: K
    Kalyx: Turmeric Root Powder, Certified Organic (Curcuma longa; Yu Jin), Frontier Herbs, 1.9 oz: K
    Kalyx: Turmeric Root Powder (Curcuma longa; Yu Jin), Frontier Herbs, 1.92 oz: K
    Kalyx: Turmeric Powder, Certified Organic, Simply Organic, 2.38 oz Bottle: K
    Kalyx: Turmeric (Jiang Huang) Granules, Evergreen, 3.5 oz: V
    Kalyx: Turmeric Root Powder, Certified Organic (Curcuma longa; Yu Jin), Starwest Botanicals, 3.5 oz: C
    Kalyx: Turmeric Rhizome (Curcuma longa; Jiang Huang) Granules, Sun Ten, 100 grams (3.5 oz): V (Special Order)
    Kalyx: Turmeric Rhizome (Curcuma longa, Yu Jin) Granules, Sun Ten, 100 grams (3.5 oz): V (Special Order)
    Kalyx: Turmeric Rhizome (Curcuma longa; Jiang Huang) 5:1 Extract Powder, Plum Flower, 100 grams (3.5 oz): V (Special Order)
    Kalyx: Turmeric Rhizome (Curcuma longa; Yu Jin) 5:1 Extract Powder, Plum Flower, 100 grams (3.5 oz): V (Special Order)
    Kalyx: Turmeric Root Sliced, Certified Organic, Starwest Botanicals, 1 lb: C
    Kalyx: Turmeric Root Powder, Starwest Botanicals, 1 lb: C
    Kalyx: Turmeric Root Powder, Certified Organic, Starwest Botanicals, 1 lb: C
    Kalyx: Turmeric Root Powder, Wildcrafted (Curcuma longa; Yu Jin), Vadik Herbs, 1 lb: B
    Kalyx: Turmeric Root Powder, Certified Organic (Curcuma longa; Yu Jin), Frontier Brand, 1 lb: K
    Kalyx: Turmeric Root Powder, Alleppey, 5% Curcumin (Curcuma longa; Yu Jin), Frontier Brand, 1 lb: K
    Kalyx: Turmeric Root Powder, Certified Organic, Fair Trade Certified (1 to 4% Curcumin), Frontier, 1 lb: K
    Kalyx: Turmeric Spice, Ground, Charleston Nut Company, 22 oz: GN
    Kalyx: Turmeric Rhizome (Curcuma longa rhizome; Jiang Huang) Whole, Plum Flower, 500 grams (1.17 lb): V (Special Order)
    Kalyx: Turmeric Rhizome (Curcuma longa tuber; Yu Jin) Whole, Plum Flower, 500 grams (1.17 lb): V (Special Order)
    Kalyx: Turmeric Tuber (Curcuma longa; Yu Jin) Powdered, Plum Flower, 500 grams (1.17 lb): V (Special Order)
    Kalyx: Turmeric Rhizome (Curcuma longa rhizome; Jiang Huang) Powder, Plum Flower, 500 grams (1.17 oz): V (Special Order)
    Kalyx: Turmeric Root Powder, Kalyx Bulk Products, 1 Kg (2.2 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 95% Curcuminoids, Kalyx Bulk Products, 1 Kg (2.2 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 50% Curcuminoids, Kalyx Bulk Products, 1 Kg (2.2 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract (Curcuma longa, Jiang Huang), Kalyx Bulk Products, 1 Kg (2.2 lbs): EB
    Kalyx: Turmeric (Ground), Spiceco, 5 lb: GR
    Ground turmeric comes from the fingers of the root of a leafy plant in the ginger family. This spice is mildly aromatic with scents of orange or ginger and has a pungent, bitter flavor. Turmeric is a necessary ingredient of curry powder and is used extensively in Indian dishes as well as Southeast Asian cuisine. It is also added to mustard blends and relishes and can be used in place of saffron to provide color and flavor. Each case consists of five pounds.
    Kalyx: Turmeric Root Powder, Kalyx Bulk Products, 5 Kg (11 lbs): EB
    Kalyx: Turmeric Root Curcumin 95%, Kalyx Bulk Products, 5 Kg (11 lbs): TN
    Kalyx: Turmeric Root Powder Extract, 95% Curcuminoids, Kalyx Bulk Products, 5 Kg (11 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 50% Curcuminoids, Kalyx Bulk Products, 5 Kg (11 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract, Kalyx Bulk Products, 5 Kg (11 lbs): EB
    Kalyx: Turmeric Root Powder, Kalyx Bulk Products, 1 Kg (2.2 lbs): EB
    Kalyx: Turmeric Root Curcumin 95%, Kalyx Bulk Products, 10 Kg (22 lbs): TN
    Kalyx: Turmeric Root Powder Extract, 95% Curcuminoids, Kalyx Bulk Products, 10 Kg (22 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 50% Curcuminoids, Kalyx Bulk Products, 10 Kg (22 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract (Curcuma longa, Jiang Huang), Kalyx Bulk Products, 10 Kg (22 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract, 10% Curcuminoids, Kalyx Bulk Products, 10 Kg (22 lbs): NG
    Kalyx: Turmeric Root Powder Extract, 20% Curcuminoids, Kalyx Bulk Products, 10 Kg (22 lbs): NG
    Kalyx: Turmeric (Ground), Van De Vries, 25 lb: GR
    Kalyx: Turmeric Root Powder, Certified Organic (Curcuma longa; Yu Jin), Starwest Botanicals, 25 lb Box: C
    Kalyx: Turmeric Root Sliced, Certified Organic, Kalyx Bulk Products, 50 lbs (22.73 Kg): CO
    Kalyx: Turmeric Root Teacut, Certified Organic, Kalyx Bulk Products, 50 lbs (22.73 Kg): CO
    Kalyx: Turmeric Root Ground, Certified Organic, Kalyx Bulk Products, 50 lbs (22.73 Kg): CO
    Kalyx: Turmeric Root Powder, Kalyx Bulk Products, 25 Kg (55 lbs): EB
    Kalyx: Turmeric Root Powder (Curcuma longa), Kalyx Bulk Products, 25 Kg (55 lbs): GE
    Kalyx: Turmeric Root Powder, Certified Organic, Kalyx Bulk Products, 25 Kg (55 lbs): GV
    Kalyx: Turmeric Root Powder, Wildcrafted (Curcuma longa; Yu Jin), Vadik Herbs, 25 Kg (55 lbs): B
    Kalyx: Turmeric Root Standardized Extract Powder, 97% Curcuminoids (Curcuma longa), Kalyx Bulk Products, 25 Kg (55 lbs): GF
    Kalyx: Turmeric Root Curcumin 95%, Kalyx Bulk Products, 25 Kg (55 lbs): TN
    Kalyx: Turmeric Root Standardized Extract Powder, 95% Curcuminoids (Curcuma longa), Kalyx Bulk Products, 25 Kg (55 lbs): GF
    Kalyx: Turmeric Root Powder Extract, 95% Curcuminoids, Kalyx Bulk Products, 25 Kg (55 lbs): NG
    Kalyx: Turmeric Root Extract Powder, 95% Curcuminoids (Curcuma longa; Jiang Huang), Kalyx Bulk Products, 25 Kg (55 lbs): HM
    Kalyx: Turmeric Root Extract Powder, 95% Curcuminoids (Curcuma longa; Jiang Huang), Kalyx Bulk Products, 25 Kg (55 lbs): HP
    Kalyx: Turmeric Root Powder Extract, 95% Curcuminoids, Kalyx Bulk Products, 25 Kg (55 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 50% Curcuminoids, Kalyx Bulk Products, 25 Kg (55 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 20% Curcuminoids, Kalyx Bulk Products, 25 Kg (55 lbs): NG
    Kalyx: Turmeric Root 4:1 Powdered Extract, Kalyx Bulk Products, 25 Kg (55 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract (Curcuma longa, Jiang Huang), Kalyx Bulk Products, 25 Kg (55 lbs): Q
    Kalyx: Turmeric Root 4:1 Powdered Extract, 10% Curcuminoids, Kalyx Bulk Products, 25 Kg (55 lbs): NG
    Kalyx: Turmeric Root, Cut & Sifted, Certified Organic, Kalyx Bulk Products, 82 lbs (37.27 Kg): CO
    Kalyx: Turmeric Root, Cut & Sifted, Certified Organic, Kalyx Bulk Products, 100 lbs: CO
    Kalyx: Turmeric Root Powder, Kalyx Bulk Products, 50 Kg (110 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 95% Curcuminoids, Kalyx Bulk Products, 50 Kg (110 lbs): EB
    Kalyx: Turmeric Root Powder Extract, 50% Curcuminoids, Kalyx Bulk Products, 50 Kg (110 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract, Kalyx Bulk Products, 50 Kg (110 lbs): EB
    Kalyx: Turmeric Root Powder, Kalyx Bulk Products, 100 Kg (220 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract, Kalyx Bulk Products, 100 Kg (220 lbs): EB
    Kalyx: Turmeric Root Powder, Kalyx Bulk Products, 200 Kg (440 lbs): EB
    Kalyx: Turmeric Root 4:1 Powdered Extract, Kalyx Bulk Products, 200 Kg (440 lbs): EB
    Kalyx: Turmeric Root, Cut & Sifted, Certified Organic, Kalyx Bulk Products, 500 Kg (1100 lbs): HW
    Kalyx: Turmeric Root Powder, Certified Organic, Kalyx Bulk Products, 500 Kg (1100 lbs): HW


    Liquid Extracts

    Kalyx: Turmeric Rhizome (Jiang Huang) Glycerin Fluid Extract, Golden Lotus, 2 fl oz: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Single Herb Alcohol Fluid Extract, Golden Lotus, 2 fl oz: GL
    Kalyx: Turmeric Tuber (Yu Jin) Single Herb Alcohol Fluid Extract, Golden Lotus, 2 fl oz: GL
    Kalyx: Turmeric Root Extract (Curcuma longa; Yu Jin), Health & Herbs, 2 fl oz: HH
    Kalyx: Turmeric Root Non-Alcoholic Extract (Curcuma longa; Yu Jin), Health & Herbs, 2 fl oz: HH
    Kalyx: Turmeric Rhizome (Jiang Huang) Glycerin Fluid Extract, Golden Lotus, 4 fl oz: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Single Herb Alcohol Fluid Extract, Golden Lotus, 4 fl oz: GL
    Kalyx: Turmeric Tuber (Yu Jin) Single Herb Alcohol Fluid Extract, Golden Lotus, 4 fl oz: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Glycerin Fluid Extract, Golden Lotus, 8 fl oz: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Single Herb Alcohol Fluid Extract, Golden Lotus, 8 fl oz: GL
    Kalyx: Turmeric Tuber (Yu Jin) Single Herb Alcohol Fluid Extract, Golden Lotus, 8 fl oz: GL
    Kalyx: Turmeric Root Extract (Curcuma longa; Yu Jin), Health & Herbs, 8 fl oz: HH
    Kalyx: Turmeric Root Non-Alcoholic Extract (Curcuma longa; Yu Jin), Health & Herbs, 8 fl oz: HH
    Kalyx: Turmeric Rhizome (Jiang Huang) Glycerin Fluid Extract, Golden Lotus, 16 fl oz: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Single Herb Alcohol Fluid Extract, Golden Lotus, 16 fl oz: GL
    Kalyx: Turmeric Tuber (Yu Jin) Single Herb Alcohol Fluid Extract, Golden Lotus, 16 fl oz: GL
    Kalyx: Turmeric Root Extract (Curcuma longa; Yu Jin), Health & Herbs, 16 fl oz: HH
    Kalyx: Turmeric Root Non-Alcoholic Extract (Curcuma longa; Yu Jin), Health & Herbs, 16 fl oz: HH
    Kalyx: Turmeric Rhizome (Jiang Huang) Glycerin Fluid Extract, Golden Lotus, 32 fl oz: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Single Herb Alcohol Fluid Extract, Golden Lotus, 32 fl oz: GL
    Kalyx: Turmeric Tuber (Yu Jin) Single Herb Alcohol Fluid Extract, Golden Lotus, 32 fl oz: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Glycerin Fluid Extract, Golden Lotus, 1 Gallon: GL
    Kalyx: Turmeric Rhizome (Jiang Huang) Single Herb Alcohol Fluid Extract, Golden Lotus, 1 Gallon: GL
    Kalyx: Turmeric Tuber (Yu Jin) Single Herb Alcohol Fluid Extract, Golden Lotus, 1 Gallon: GL


    AMAZON PRODUCTS

    Amazon: Curcumin Supplement Products
    Amazon: Turmeric Herbal Supplement Products
    Amazon: Turmeric Herbal Grocery & Gourmet Food Products

  • Nutrition Basics: Curcumin (Turmeric) Antioxidant Information
  • Nutrition Basics: Turmeric (Curcumin) Herbal Information






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    AROMATHERAPY: ESSENTIAL OILS DESCRIPTIONS & USES


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    Aromatherapy
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    Using Essential Oils


    AROMATHERAPY: HERBAL & CARRIER OILS DESCRIPTIONS & USES


    Almond, Sweet Oil
    Apricot Kernel Oil
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