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Serine was first isolated in 1865 from sericin, a silk protein, and is a non-essential amino acid.
Serine is needed for the proper metabolism of fats and fatty acids, the growth of muscle, and the maintenance of a healthy immune system. It aids in the production of immuneglobulins and antibodies. Serine can be synthesized from glycine in the body. It is a constituent of brain proteins and nerve coverings and is also important in the formation of cell membranes, involved in the metabolism of purines and pyrimidines. It is included as a natural moisturizing agent in many cosmetics and skin care preparations. Some derivatives (e.g. ethanolamine) are also important components of the phospholipids found in biological membranes.
SOURCES
Serine is found in meats and dairy products, wheat gluten, peanuts as well as soy products. Its production requires adequate amounts of B-3 (niacin), B-6, and Folic acid.
MOLECULAR DESCRIPTION
The methyl side chain of serine contains a hydroxy group making this one of two amino acids that are also alcohols. Serine plays a major role in a variety of biosynthetic pathways including those involving pyrimidines, purines, creatine, and porphyrins. Serine is also found at the active site in an important class of enzymes termed "serine proteases" that include trypsin and chymotrypsin. These enzymes catalyze the hydrolysis of peptide bonds in polypeptides and proteins, a major function in the digestive process. On a molar basis, serine is incorporated into proteins at a rate of 7.1 percent compared to the other amino acids.
TOXICITY & SYMPTOMS OF HIGH INTAKE
Although toxicity has not been established it has been found that very elevated serine levels may cause immune suppression and psychological symptoms as in cerebral allergies.
SERINE SUPPLEMENTS & PRODUCTS
Phosphatidyl Serine (PS), Nature's Way, 500 mg, 60 Softgels
Phosphatidyl Serine complex aids brain cell function and reduces age-related mental decline. With age normal brain and nerve cell activity may decline due to diminished neurotransmitter and brain cell function. Phosphatidyl Serine assists in regulating membrane transfer of nutrients an neurotransmitters necessary for proper mental function. Phosphatidyl Serine can provide relatively quick benefits especially to mature adults who are experiencing age related mental decline which may be associated with the early onset of Alzheimer's, dementia, senility, memory loss, and cognitive function. This product is a complex of phospholipid nutrients and fatty acids derived from soy lecithin, provided in oil soluble softgels perfect for proper delivery of this product. Recommended Daily Dosage: Take one capsule three times daily with water at mealtimes for one month. Follow by a maintenance dose of one or two capsules daily with water at mealtimes. Benefits fade away within about a month if you stop using the product.
Herbal Remedies: Phosphatidyl Serine / Serine Supplements & Products
Herbal Remedies: Phosphatidyl Serine (PS) / Serine Information
MoonDragon's Health Information: Nutrition Basics - Amino Acids Index
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