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MoonDragon's Health & Wellness
Nutrition Basics

Amino Acids
DLPA

DL-Phenylalanine


For Informational Use Only
For more detailed information contact your health care provider
about options that may be available for your specific situation.





  • DLPA Description
  • DLPA Uses, Health Benefits & Scientific Evidence
  • DLPA Dosage Information
  • DLPA Safety, Cautions & Interactions
  • DLPA Supplement Products




  • DLPA DESCRIPTION

    APPETITE SUPPRESSANT, PAIN RELIEVER & ANTIDEPRESSANT

    DL-Phenylalanine (DLPA) has been suggested for depression, pain and may help suppress appetite.

    DL-Phenylalanine (DLPA) is marketed as a nutritional supplement for its supposed analgesic and antidepressant activities. DL-Phenylalanine is a 50-50 blended mixture of D-Phenylalanine and L-Phenylalanine amino acid (building blocks for protein). The structure of the D form is used to help combat pain (salicylic acid, a component of aspirin, is biosynthesized from Phenylalanine). The structure of the L form is used as a stimulant, appetite suppressant, and mood enhancer.

    The reputed analgesic activity of DL-Phenylalanine may be explained by the possible blockage by D-phenylalanine of enkephalin degradation by the enzyme carboxypeptidase A. The mechanism of DL-phenylalanine's supposed antidepressant activity may be accounted for by the precursor role of L-Phenylalanine in the synthesis of the neurotransmitters norepinephrine and dopamine. Elevated brain levels of norepinephrine and dopamine are thought to have an antidepressant effect. D-Phenylalanine is absorbed from the small intestine and transported to the liver via the portal circulation. A small amount of D-Phenylalanine appears to be converted to L-Phenylalanine. D-Phenylalanine is distributed to the various tissues of the body via the systemic circulation. It appears to cross the blood–brain barrier less efficiently than L-Phenylalanine, and so a small amount of an ingested dose of D-phenylalanine is excreted in the urine without penetrating the central nervous system.

    DL-Phenylalanine is used by the brain to produce norepinephrine (our brains' version of adrenaline), a neurotransmitter depleted by stress, caffeine, nicotine, pollution, and some pharmacological and recreational drugs. DL-Phenylalanine also helps replace dopamine, the neurotransmitter responsible for feelings associated with sexual pleasure, confidence, and euphoria virtually side effect free.

    DL-Phenylalanine is the precursor to another amino acid called Tyrosine. Tyrosine also does all of the above except for one factor - chocolate (beta phenylethylamine), a neuromodulator associated with mood enhancement and sexual stimulation. Tyrosine does not appear to be as active in this role as chocolate and DLPA. This may be the reason some people refer to chocolate as sexual stimulant. Unfortunately, all those extra calories from consuming the amount of chocolate needed for sexual stimulation would pile-on body fat in short-order. If you are a chocoholic (for sexual stimulation or not) and want to lower your intake, phenylalanine or fasting may be the answer for you.

    DL-Phenylalanine and Caffeine - DL-Phenylalanine (or Tyrosine) works especially well with caffeine. Caffeine gives us a temporary lift by sending norepinephrine (neurotransmitter associated with mental sharpness, excitability, pain, and depression support) into the blood stream. Over time, healthy levels of norepinephrine are depleted by caffeine and other factors mentioned above if not replaced. Phenylalanine does a great job replacing this major neurotransmitter.





    DLPA USES, HEALTH BENEFITS & SCIENTIFIC EVIDENCE

    PAIN RELIEF: The pain reliever DLPA (D,L-phenylalanine) contains two forms of the amino acid phenylalanine. The "L" form is a natural substance found in Protein-rich foods; it is believed to bolster mood-elevating chemicals in the brain, such as dopamine and norepinephrine. The "D" form of phenylalanine, on the other hand, is made synthetically in a laboratory; it appears to block a nervous system Enzyme that amplifies pain signals. In other words, it may prevent the breakdown of the brain's natural narcotics. DLPA supplements combine the "L" and "D" forms of phenylalanine, packing a potent one-two punch, and quickly relieving minor depression and physical discomforts.

    WEIGHT LOSS: Many ex-smokers gain weight right after quitting and use weight gain as a reason to keep smoking. Phenylalanine encourages the hypothalamus in the brain to release CCK (cholecystokinin), the hormone responsible for signaling fullness. Using phenylalanine may eliminate ex-smokers weight gain excuse virtually side effects free.

    Note: DL-Phenylalanine should not be confused with phenylpropanolamine (a form of amphetamine). Phenylpropanolamine is an appetite depressant used in several over-the-counter diet pills. It causes the brain to use up its stores of nor-epinephrine without stimulating it to produce more. Typically, after about two weeks, the dieter stops taking the diet pill which can result in "the blues" and low energy since they are running low on norepinephrine. They then gorge themselves on food and end up gaining more weight than before.

    KICKING THE SMOKING HABIT: Have you ever wondered why cigarette smokers enjoy "lighting-up" after sex? There is evidence to support the notion that smoking appears to release dopamine into the brain. As a result, smokers appear to get a mild hit of dopamine by "lighting-up" after an orgasm. This may be one of the main reasons "kicking the smoking habit" is so difficult. Cigarette smokers may find it quite easy to become ex-smokers with the use of phenylalanine.

    COCAINE ADDICTION: Studies show that cocaine users who are trying to quit may benefit from DL-phenylalanine (DLPA), Theanine and/or Glutamine use. The chronic use of cocaine may eventually cause the side effects of depletion of dopamine and norepinephrine from the brain without replacing these two valuable neurotransmitters. As dopamine is synthesized from precursors such as DL-Phenylalanine (DLPA) and Theanine, dopamine reserves are rebuilt, thus, overcoming the problem of dopamine depletion. The use of DLPA on a regular basis may be a so-called "antidote" for those who are trying to quit cocaine. One of cocaine's principal effects is the blocking of the re-uptake of dopamine in the brain. This results in increased dopamine levels associated with the euphoric characteristic of the drug. However, chronic use of cocaine may lead to considerable dopamine reduction. In addition, cocaine users often exhibit various nutritional deficiencies (a myriad of side effects on their own). Consequently, it is strongly suggested to provide certain vitamins and minerals to one's supplement protocol, particularly Vitamin C, Pantothenic Acid (Vitamin B-5), Pyridoxal Phosphate (Vitamin B-6), Magnesium, Calcium, and Zinc. Vitamins B-6 and Vitamin C are important co-factors in the synthesis and structure of dopamine, serotonin and GABA.



    DLPA RESEARCH

    Research indicates that DLPA can be an effective part of an overall program to fight chronic pain and beat the blues, including the mood swings of premenstrual syndrome (PMS). Some sources contend that DLPA can increase energy and mental alertness, as well as heighten the ability to focus in individuals with attention deficit hyperactivity disorder (ADHD). Combined with ultraviolet (UVA) light therapy, various forms of phenylalanine have also been proposed as a treatment for vitiligo, a somewhat mysterious dermatologic condition characterized by the development of white, pigment-free patches of skin. Patients with Parkinson's disease also have experienced some relief from symptoms when taking DLPA and doing a pain relief therapy called TENS (transcutaneous electrical nerve stimulation). However, rigorous research into these uses is still needed. Specifically, DLPA may help to:

    EASE DEPRESSION. Several clinical studies have examined the effect of DLPA supplements on mood. In one trial, 12 of 20 depressed men and women who took 75 to 200 mg of DLPA a day reported being free of depression after less than three weeks of treatment, and four reported feeling somewhat better. Another early trial involving 40 depressed patients showed DLPA may be as effective as the conventional medication imipramine in treating depression. However, these studies were conducted more than two decade ago. Newer studies are needed to confirm or refute efficacy in treating depression.

    ALLAY CHRONIC PAIN. Although more research is needed, there is some evidence that DLPA can help to relieve certain types of chronic pain, including muscle aches and persistent arthritis-related pain. The supplement appears to inhibit the actions of a pain-inducing protein called enkephalinase. Some scientists speculate that DLPA also helps by boosting the effectiveness of narcotics and other pain medications. However, scientific studies have been inconclusive. In a double-blind study of 30 patients with chronic pain from various conditions that had not been relieved by several other treatments, 25-percent of patients reported more pain relief after taking 250 mg of DLPA four times a day for four weeks compared to the Placebo group. However, 22-percent of patients reported more pain relief from placebo, and 53-percent of patients reported no difference in pain relief during the study. Preliminary evidence indicates DLPA taken in conjunction with opiates for pain may increase efficacy of the conventional medications and reduce the dosage of opiates required to treat pain. More research is needed to confirm or refute efficacy in treating chronic pain.

    ENHANCE CONCENTRATION IN ADHD. DLPA has been used to enhance concentration in attention deficit-hyperactivity disorder (ADHD). Some research indicates patients with ADHD may have lower levels of Amino acids such as phenylalanine. Proponents suggest the ability of DLPA to enhance chemicals in the brain leads to improved concentration in patients with ADHD. However, research in this area has been disappointing. In a 1985 study of 19 adults with ADHD, 13 subjects who completed the study and were treated with DLPA for two weeks showed significant improvement in overall ratings and, specifically, in mood enhancement. However, all positive benefits of DLPA faded within three months of continued treatment. And in a 1987 study of 11 hyperactive boys, no changes (improvements or deterioration) in behavior were seen in the patients treated with 20 mg of DLPA daily for two weeks and placebo for two weeks. This research also is more than two decades old and requires new trials to confirm or refute efficacy.

    IMPROVE VITILIGO APPEARANCE. In combination with ultraviolet light (UVA) therapy, DLPA has been shown in several studies to activate the cells responsible for pigmentation in adults and children. Thus, by activating these cells, DLPA helps to return the white, pigment-free skin of vitiligo back to its original color. Both oral and topical formulations have shown efficacy. A review of studies has shown doses lower than 50 mg of oral DLPA daily plus UVA therapy improved pigmentation in as much as 70-percent of vitiligo spots in one open trial of 149 patients, up to 60-percent in a double-blind trial of 32 patients, and up to 50-percent in another open trial of 20 patients. In a study of 13 children treated with oral DLPA and UVA therapy, three children experienced re-pigmentation of all vitiliginous areas, six showed 50 to 90-percent improvement, and four failed to respond. In a 2002 study of 70 patients treated with 100 mg of oral DLPA plus 10-percent L-phenylalanine topical gel and exposed to sunlight or UVA lamps for six months, more than 90% of patients showed improvement in vitiligo, with more than two-thirds of those patients achieving re-pigmentation in at least 75-percent of vitiliginous areas (primarily on the face). A 2008 review of 15 trials evaluating natural vitiligo treatments found that all trials involving DLPA in conjunction with light therapy reported beneficial findings and that it warrants further investigation.

    REDUCE PARKINSON'S DISEASE SYMPTOMS. Limited research indicates DLPA may help to improve rigidity, walking, speech and depression associated with Parkinson's disease. More research is needed to determine efficacy in treating symptoms of Parkinson's disease.


    REFERENCES

    1. Beckmann H, Strauss MA, Ludolph E. DL-phenylalanine in depressed patients: an open study. J Neural Transm. 1977;41(2-3):123-34.
    2. Beckmann H, Athen D, Olteanu M, et al. DL-phenylalanine versus imipramine: a double-blind controlled study. Arch Psychiatr Nervenkr. 1979 Jul 4;227(1):49-58.
    3. Walsh NE, Ramamurthy S, Schoenfeld L, Hoffman J. Analgesic effects of D-phenylalanine in chronic pain patients. Arch Phys Med Rehabil. 1986 Jul;67(7):436-9.
    4. Russell AL, McCarty MF. DL-phenylalanine markedly potentiates opiate analgesia – an example of nutrient/pharmaceutical up-regulation of the endogenous analgesia system. Med Hypotheses. 2000 Oct;55(4):283-8.
    5. Bornstein RA, Baker GB, Carroll A, et al. Plasma amino acids in attention deficit disorder. Psychiatry Res. 1990;33:301-6.
    6. Wood DR, Reimherr FW, Wender PH. Treatment of attention deficit disorder with DL-phenylalanine. Psychiatry Res. 1985 Sep;16(1):21-6.
    7. Zametkin AJ, Karoum F, Rapoport JL. Treatment of hyperactive children with D-phenylalanine. Am J Psychiatry. 1987 Jun;144(6):792-4.
    8. Thiele B, Steigleder GK. Repigmentation treatment of vitiligo with L-phenylalanine and UVA irradiation. Z Hautkr. 1987 Apr 1;62(7):519-23.
    9. Antoniou C, Schulpis H, Michas T, et al. Vitiligo therapy with oral and topical phenylalanine with UVA exposure. Int J Dermatol. 1989;28:545-7.
    10. Siddiqui AH, Stolk LM, Bhaggoe R, et al. L-phenylalanine and UVA irradiation in the treatment of vitiligo. Dermatology. 1994;188(3):215-8.
    11. Schulpis CH, Antoniou C, Michas T. Phenylalanine plus ultraviolet light: preliminary report of a promising treatment for childhood vitiligo. Pediatr Dermatol. 1989 Dec;6(4):332-5.
    12. Camacho F, Mazuecos J. Oral and topical L-phenylalanine, clobetasol propionate, and UVA/sunlight – a new study for the treatment of vitiligo. J Drugs Dermatol. 2002 Sep;1(2):127-31.
    13. Szczurko O, Boon HS. A systematic review of natural health product treatment for vitiligo. BMC Dermatol. 2008 May 22;8:2.
    14. Heller B, Fischer BE, Martin R. Therapeutic action of D-phenylalanine in Parkinson's disease. Arzneimittelforschung. 1976;26:577-9.





    DLPA DOSAGE INFORMATION

    SUPPLEMENT FORMS

    DLPA nutritional supplements are available in the form of capsules and tablets.

    DL-Phenylalanine competes with other amino acids. They have to be able to pass through the stomach and blood brain barrier without competition. The consensus of experts recommend taking Phenylalanine on an empty stomach 15 to 20 minutes before eating. Avoid taking them with other amino acids multi-formula or other supplement formulas. It is recommended to start with 500 to 1,000 mg as soon as you awake. Some people take another 500 to 1,000 mg 4 to 6 hours later for that extra "lift." As a possible side effect, taking it too close to bedtime may keep you awake. Some people build up (after taking lower doses for a couple of weeks) to 2,000 mg in the morning and 2,000 mg in the evening.

    There has to be significant amounts of Vitamin B-6 and Vitamin C present in your blood stream in order for Phenylalanine (or Tyrosine) to work. The ingestion of 150 to 200 mg of Vitamin B-6 and 3,000 to 4,000 mg of Vitamin C divided throughout the day does a great job.

  • DL-Phenylalanine (DLPA) Supplements & Products
  • Phenylalanine / L-Phenylalanine Supplements & Products
  • Amino Acid Complex Supplements & Products
  • Vitamin B-6 Supplement Products
  • Vitamin C Supplement Products

  • SPECIAL TIPS

  • Look for formulations that contain both the "D" and "L" forms of the amino acid phenylalanine. This combination is less likely to lead to high blood pressure than using the natural "L" form alone.
  • If you have high blood pressure, start with very low amounts, such as 100 mg a day. Increase the dose slowly and only under a health care practitioners supervision.
  • As is the case with most dietary supplements, DLPA has not been studied in pregnant or breast-feeding women, those with kidney or liver disease, and in only very limited fashion in children. Safety and proper dosing in these groups has not been established.

  • AILMENTS DOSAGE

  • Chronic Pain: Up to 1,500 mg daily, in 2 or 3 divided doses between meals, taken on an empty stomach.
  • Depression Relief: 200 mg a day, taken in the morning.
  • ADHD: 20 mg daily has been used.
  • Vitiligo: 50 to 100 mg oral DLPA daily along with UVA exposure, and/or a 10-percent phenylalanine topical cream along with UVA exposure has been used.
  • Parkinson's Disease: 200 to 500 mg oral DLPA has been used.

  • GUIDELINES FOR USE

    As with other amino acid supplements, it is best to take DLPA on an empty stomach with water or juice about an hour before meals. High-protein foods, in particular, can interfere with proper absorption.

    Store in a cool, dry place, such as a closet shelf away from heat, light, and moisture. (Avoid the humid bathroom medicine cabinet.)





    DLPA SAFETY, CAUTIONS & INTERACTION INFORMATION

    SIDE EFFECTS

  • At recommended doses, DLPA occasionally causes mild side effects, such as heartburn, nausea, or headaches. At excessive doses (more than 1,500 mg a day), it can cause numbness, tingling, or other signs of nerve damage.
  • DLPA may have the unwanted effect of raising blood pressure, although the D, L combination form is less likely to do so than supplements containing only the "L" form of the amino acid.
  • Insomnia may be a side effect if taken too close to bedtime.

  • WARNINGS

  • Keep out of reach of children.
  • Do not exceed recommended dose.
  • If you have a bad reaction or side effects, discontinue use immediately.
  • When using DL-Phenylalanine (DLPA), please inform your health care provider.

  • CAUTIONS

  • Use DLPA under the supervision of a health care practitioner familiar with its use. When taken in high doses (greater than 1,500 mg a day) over prolonged periods of time, nerve damage may develop. Lower doses appear to be safe.
  • Supplemental use of L-phenylalanine and L-tyrosine may raise or normalize blood pressure. For those with high blood pressure or who are prone to anxiety or panic attacks, DLPA could seriously aggravate the condition. Let a health care provider know if signs or symptoms worsen while taking DLPA.
  • Pregnant women should not take DLPA, since it has not been well studied in this group.
  • Cancer patients should avoid taking L-phenylalanine and L-tyrosine. Certain cancers, such as melanoma, depend on these amino acids to fuel their growth. For people who have been diagnosed with malignant melanoma, a potentially deadly form of skin cancer, some health care practitioners caution against taking DLPA. There has been some concern that phenylalanine could stimulate the pigment producing cancer cells, although the connection, if any, remains unclear.
  • Persons with phenylketonuria (PKU), a rare, inherited metabolic disorder should avoid taking DLPA, as they lack an enzyme that converts phenylalanine to tyrosine and must follow very strict dietary guidelines to prevent toxic damage to the nervous system.


  • PHENYLKETONURIA (PKU)


    Phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood. Phenylalanine is a building block of proteins (an amino acid) that is obtained through the diet. It is found in all proteins and in some artificial sweeteners. If PKU is not treated, phenylalanine can build up to harmful levels in the body, causing intellectual disability and other serious health problems.

    PKU SYMPTOMS

    The signs and symptoms of PKU vary from mild to severe. The most severe form of this disorder is known as classic PKU. Infants with classic PKU appear normal until they are a few months old. Without treatment with a special low-phenylalanine diet, these children develop permanent intellectual disability. Seizures, delayed development, behavioral problems, and psychiatric disorders are also common. Untreated individuals may have a musty or mouse-like odor as a side effect of excess phenylalanine in the body.

    Children with classic PKU tend to have lighter skin and hair than unaffected family members and are also likely to have skin disorders such as eczema. Less severe forms of this condition, sometimes called variant PKU and non-PKU hyperphenylalaninemia, have a smaller risk of brain damage. People with very mild cases may not require treatment with a low-phenylalanine diet. Babies born to mothers with PKU and uncontrolled phenylalanine levels (women who no longer follow a low-phenylalanine diet) have a significant risk of intellectual disability because they are exposed to very high levels of phenylalanine before birth. These infants may also have a low birth weight and grow more slowly than other children. Other characteristic medical problems include heart defects or other heart problems, an abnormally small head size (microcephaly), and behavioral problems. Women with PKU and uncontrolled phenylalanine levels also have an increased risk of pregnancy loss.

    The occurrence of PKU varies among ethnic groups and geographic regions worldwide. In the United States, PKU occurs in 1 in 10,000 to 15,000 newborns. Most cases of PKU are detected shortly after birth by newborn screening, and treatment is started promptly. As a result, the severe signs and symptoms of classic PKU are rarely seen.

    PKU GENETIC RELATION

    Mutations in the PAH gene cause phenylketonuria. The PAH gene provides instructions for making an enzyme called phenylalanine hydroxylase. This enzyme converts the amino acid phenylalanine to other important compounds in the body. If gene mutations reduce the activity of phenylalanine hydroxylase, phenylalanine from the diet is not processed effectively. As a result, this amino acid can build up to toxic levels in the blood and other tissues. Because nerve cells in the brain are particularly sensitive to phenylalanine levels, excessive amounts of this substance can cause brain damage.

    Classic PKU, the most severe form of the disorder, occurs when phenylalanine hydroxylase activity is severely reduced or absent. People with untreated classic PKU have levels of phenylalanine high enough to cause severe brain damage and other serious medical problems. Mutations in the PAH gene that allow the enzyme to retain some activity result in milder versions of this condition, such as variant PKU or non-PKU hyperphenylalaninemia.

    Changes in other genes may influence the severity of PKU, but little is known about these additional genetic factors.

    This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

    Phenylketonuria. is also known as:
    • Deficiency Disease, Phenylalanine Hydroxylase
    • Folling Disease
    • Folling's Disease
    • Phenylalanine Hydroxylase Deficiency Disease
    • PAH Deficiency
    • PKU


    GENERAL INTERACTIONS

  • Because DLPA exerts its effects through the central nervous system, avoid taking it with prescription antidepressants or stimulants, unless specifically instructed to do so by a health care provider.
  • Some research indicates that DLPA can exacerbate facial tics and other symptoms of tardive dyskinesia, a troubling movement disorder caused by long-term use of antipsychotic medicines. Stop taking DLPA and consult a health care provider for concerns about reactions to DLPA.
  • As with other Amino acids, DLPA may interfere with the effects of levodopa, a drug commonly used to treat Parkinson's disease. Do not combine the two.

  • DLPA DRUG INTERACTIONS

  • Amitriptyline Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with amitriptyline, unless specifically instructed to do so by your health care provider.
  • Bupropion Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with bupropion, unless specifically instructed to do so by your health care provider.
  • Desipramine Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with desipramine, unless specifically instructed to do so by your health care provider.
  • Escitalopram Oxalate: Because DLPA exerts its effects through the central nervous system, avoid taking it with escitalopram, unless specifically instructed to do so by your health care provider.
  • Levodopa: DLPA may interfere with the effects of levodopa, a drug commonly used to treat Parkinson's disease. Do not combine the two.
  • Minocycline: Because DLPA exerts its effects through the central nervous system, avoid taking it with mirtazapine, unless specifically instructed to do so by your health care provider.
  • Paroxetine Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with paroxetine, unless specifically instructed to do so by your health care provider.
  • Sertraline Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with sertraline, unless specifically instructed to do so by your health care provider.
  • Tranylcypromine Sulfate: Because DLPA exerts its effects through the central nervous system, avoid taking it with tranylcypromine, unless specifically instructed to do so by your health care provider.
  • Trazodone: Because DLPA exerts its effects through the central nervous system, avoid taking it with trazodone, unless specifically instructed to do so by your health care provider.
  • Venlafaxine: Because DLPA exerts its effects through the central nervous system, avoid taking it with venlafaxine, unless specifically instructed to do so by your health care provider.
  • Pemoline: Because DLPA exerts its effects through the central nervous system, avoid taking it with pemoline, unless specifically instructed to do so by your health care provider.
  • Phenelzine Sulfate: Because DLPA exerts its effects through the central nervous system, avoid taking it with phenelzine, unless specifically instructed to do so by your health care provider.
  • Protriptyline Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with protriptyline, unless specifically instructed to do so by your health care provider.
  • Levodopa / Carbidopa: DLPA may interfere with the effects of levodopa, a drug commonly used to treat Parkinson's disease. Do not combine the two.
  • Maprotiline Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with maprotiline, unless specifically instructed to do so by your health care provider.
  • Methamphetamine Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with methamphetamine, unless specifically instructed to do so by your health care provider.
  • Methylphenidate Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with methylphenidate, unless specifically instructed to do so by your health care provider.
  • Fluoxetine Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with fluoxetine, unless specifically instructed to do so by your health care provider.
  • Fluvoxamine Maleate: Because DLPA exerts its effects through the central nervous system, avoid taking it with fluvoxamine, unless specifically instructed to do so by your health care provider.
  • Imipramine: Because DLPA exerts its effects through the central nervous system, avoid taking it with imipramine, unless specifically instructed to do so by your health care provider.
  • Nefazodone Hydrochloride: Because DLPA exerts its effects through the central nervous system, avoid taking it with nefazodone, unless specifically instructed to do so by your health care provider.
  • Nortriptyline Hydrochloride Because DLPA exerts its effects through the central nervous system, avoid taking it with nortriptyline, unless specifically instructed to do so by your health care provider.
  • Caffeine Because DLPA exerts its effects through the central nervous system, avoid taking it with caffeine, unless specifically instructed to do so by your health care provider.
  • Citalopram Hydrobromide Because DLPA exerts its effects through the central nervous system, avoid taking it with citalopram, unless specifically instructed to do so by your health care provider.
  • Clomipramine Hydrochloride Because DLPA exerts its effects through the central nervous system, avoid taking it with clomipramine, unless specifically instructed to do so by your health care provider.
  • Amlodipine Because DLPA exerts its effects through the central nervous system, avoid taking it with amoxapine, unless specifically instructed to do so by your health care provider.
  • Amphetamine Because DLPA exerts its effects through the central nervous system, avoid taking it with amphetamine, unless specifically instructed to do so by your health care provider.
  • Amphetamine/Dextroamphetamine Because DLPA exerts its effects through the central nervous system, avoid taking it with this drug combination, unless specifically instructed to do so by your health care provider.
  • Dextroamphetamine Sulfate Because DLPA exerts its effects through the central nervous system, avoid taking it with dextroamphetamine, unless specifically instructed to do so by your health care provider.
  • Diethylpropion Hydrochloride Because DLPA exerts its effects through the central nervous system, avoid taking it with diethylpropion, unless specifically instructed to do so by your health care provider.
  • Doxepin Hydrochloride Because DLPA exerts its effects through the central nervous system, avoid taking it with doxepin, unless specifically instructed to do so by your health care provider.
  • Ephedrine: Because DLPA exerts its effects through the central nervous system, avoid taking it with ephedrine, unless specifically instructed to do so by your health care provider.





  • DLPA AMINO ACID SUPPLEMENT PRODUCTS

  • DLPA Amino Acid Products
  • Phenylalanine Amino Acid Products

  • Amino Acid Complex Supplement Products



  • QUALITY SUPPLIES & PRODUCTS


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    DLPA (DL-PHENYLALANINE) AMINO ACID SUPPLEMENT PRODUCTS

    Amino acids are the building blocks of protein. In fact, the daily protein requirement is really the body’s need for amino acids. Dietary amino acids are classified as essential and non-essential. Both are used to assemble hormones, enzymes neurotransmitters (chemical messengers), antibodies, and nutrient carriers. The pain reliever DLPA (DL-phenylalanine) contains two forms of the amino acid phenylalanine (the L form) and its mirror image (the D form). DLPA may have the unique ability to block the enzyme (enkephalinase) in the central nervous system that is responsible for breaking down natural, morphine-like hormones called endorphins and enkephalins. DLPA is a natural substance found in protein-rich foods its believed to bolster mood-elevating chemicals in the brain. That means, in addition to pain relief, DLPA has been credited with balancing mood, increasing alertness and improving memory.

    HERBSPRO PRODUCTS

    HerbsPro: DL-Phenylalanine, Support An Alert State, 375 mg, 60 Tabs (6797)
    HerbsPro: DL-Phenylalanine, Support An Alert State, 375 mg, 120 Tabs (6798)
    HerbsPro: DL-Phenylalanine (DLPA), BlueBonnet Nutrition, 500 mg, 30 VCaps (100404)
    HerbsPro: DL-Phenylalanine (DLPA), Solgar, 500 mg, 50 VCaps (36359)
    HerbsPro: DL-Phenylalanine (DLPA), Thompson Nutritional Products, 500 mg, 60 Caps (38815)
    HerbsPro: DL-Phenylalanine (DLPA), BlueBonnet Nutrition, 500 mg, 60 VCaps (100405)
    HerbsPro: DL-Phenylalanine (DLPA), Solgar, 500 mg, 100 VCaps (36358)
    HerbsPro: DL-Phenylalanine, Source Naturals, 750 mg, 30 Tabs (6799)
    HerbsPro: DL-Phenylalanine, Source Naturals, 750 mg, 60 Tabs (6800)
    HerbsPro: DL-Phenylalanine (DLPA), FoodScience of Vermont, 750 mg, 60 Caps (66160)
    HerbsPro: DL-Phenylalanine (DPLA), Country Life, 1000 mg, 30 Caps (37141)
    HerbsPro: DL-Phenylalanine (DPLA), Country Life, 1000 mg, 60 Caps (37142)


    AMAZON PRODUCTS

    Amazon: DL-Phenylalanine Amino Acid Supplement Products
    Amazon: DLPA Amino Acid Supplement Products

  • Nutrition Basics: DLPA (DL-Phenylalanine) Amino Acid Information
  • Nutrition Basics: Phenylalanine Amino Acid Information



  • PHENYLALANINE (L-PHENYLALANINE) SUPPLEMENT PRODUCTS

    L-Phenylalanine is an essential amino acid that can be readily converted into the amino acid Tyrosine. Because Tyrosine is necessary for the synthesis of proteins and the production of the neurotransmitters dopamine and norepinephrine, Phenylalanine is an extremely important nutrient that must be obtained through the diet or supplementation. An essential neurotransmitter that promotes vitality and alertness. Usual recommended dosage is 500 mg daily on an empty stomach, or as directed by your health care provider. Caution: Do not take the supplement if you are pregnant or nursing, or if you suffer from panic attacks, diabetes, high blood pressure, or PKU.

    HERBSPRO PRODUCTS

    HerbsPro: L-Phenylalanine Powder, An Essential Amino Acid, Source Naturals, 100 grams (3.53 oz.) (7055)
    HerbsPro: L-Phenylalanine, Thompson Nutritional Products, 500 mg, 30 Caps (35640)
    HerbsPro: L-Phenylalanine, BlueBonnet Nutrition, 500 mg, 30 VCaps (100424)
    HerbsPro: L-Phenylalanine, Natures Life, 500 mg, 50 Caps (89900)
    HerbsPro: L-Phenylalanine, Solgar, 500 mg, 50 VCaps (36582)
    HerbsPro: L-Phenylalanine, TwinLab, 500 mg, 60 Caps (19684)
    HerbsPro: L-Phenylalanine With B-6, Country Life, 500 mg, 60 Caps (37279)
    HerbsPro: L-Phenylalanine, BlueBonnet Nutrition, 500 mg, 60 VCaps (100425)
    HerbsPro: L-Phenylalanine, Now Foods, 500 mg, 60 Caps (68604)
    HerbsPro: L-Phenylalanine, Solgar, 500 mg, 100 VCaps (36581)
    HerbsPro: L-Phenylalanine, Now Foods, 500 mg, 120 Caps (68603)


    AMAZON PRODUCTS

    Amazon: Phenylalanine Amino Acid Supplement Products

  • Nutrition Basics: DLPA (DL-Phenylalanine) Amino Acid Information
  • Nutrition Basics: Phenylalanine Amino Acid Information



  • AMINO ACID COMPLEX PRODUCTS

    HERBSPRO PRODUCTS

    HerbsPro: Amino-9 Essentials Powder, Now Foods, 330 Grams
    Complete Free Form blend of all 9 essential amino acids. Dietary supplements helpful in sports. GMP quality assured.
    HerbsPro: Amino Balance Powder, Free Form Amino Acid Complex, Anabol Naturals
    HerbsPro: Amino Balance Powder, Free Form Amino Acid Complex, Anabol Naturals, 500 grams
    HerbsPro: Amino Balance, Free Form Amino Acid Complex, Anabol Naturals, 500 mg, 120 Caps
    HerbsPro: Amino Balance, Free Form Amino Acid Complex, Anabol Naturals, 500 mg, 240 Caps
    HerbsPro: Amino Balance, Free Form Amino Acid Complex, Anabol Naturals, 500 mg, 500 Caps
    For tissue repair, reduced soreness and accelerated recovery, as well as a wealth of non-training benefits, this blend of 23 pure crystalline 100% pharmaceutical grade free-form amino acids is unmatched.
    HerbsPro: Amino Max 21, FoodScience of Vermont, 90 Caps
    A high quality, hypoallergenic amino acid formulation. Amino Max 21 is a scientifically formulated combination of 21 crystalline, free-form amino acids in the natural L-configuration. Because free-form amino acids are readily bioavailable and require no digestion by the body, they can be absorbed efficiently into the bloodstream and accompanying tissues where they are used for cellular regeneration.
    HerbsPro: Essential Amino Acid Complex, Solgar, Free Form, 600 mg, 90 VCaps (36384)
    HerbsPro: Amino Complete, Balanced Blend Complex, Now Foods, 120 Caps
    HerbsPro: Max-Amino With Vitamin B-6, Blend of 18 Amino Acids, Country Life, 180 Caps
    An easily absorbed blend of 18 amino acids yielding high biological activity. An ideal formula for athletes, and when protein demands may not be fully satisfied. B-6 aids in the utilization of amino acids. An easily absorbed Amino Acid Supplement.
    HerbsPro: Amino Acid Complete, Balanced Blend Complex, Now Foods, 360 Caps
    HerbsPro: Cher-Amino Liquid Protein, TwinLab, 16 fl. oz. (19499)
    Cher Amino Protein is a concentrated and peptide bonded free amino acid supplement contains all essential amino acid derived from natural enzyme hydrolysis of collagen protein and whey protein that help relieve muscle breakdown.
    HerbsPro: Cher-Amino Liquid Protein, TwinLab, 32 fl. oz. (19498)
    Cher Amino Protein is a concentrated and peptide bonded free amino acid supplement contains all essential amino acid derived from natural enzyme hydrolysis of collagen protein and whey protein that helps to relieve muscle breakdown. The protein in this product is a predigested collagen and whey (lactalbumin) protein and is therefore utilized 100%. Contains all the essential amino acids derived by enzymatically hydrolyzing the animal protein collagen and whey protein (lactalbumin). The amino acids in this product are naturally present in the protein. They are not added or manufactured. 15 grams per ounce. New improved formula. Predigested collagen. Enriched with predigested whey protein, a superior source of high quality amino acids.


    AMAZON PRODUCTS

    Amazon: Amino Acid Complex Complete Supplement Products

  • Nutrition Basics: Amino Acid Complex Supplement Information






  • MoonDragon's Womens Health Index

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    Health & Wellness Index





    AROMATHERAPY: ESSENTIAL OILS DESCRIPTIONS & USES


    Allspice Leaf Oil
    Angelica Oil
    Anise Oil
    Baobab Oil
    Basil Oil
    Bay Laurel Oil
    Bay Oil
    Benzoin Oil
    Bergamot Oil
    Black Pepper Oil
    Chamomile (German) Oil
    Cajuput Oil
    Calamus Oil
    Camphor (White) Oil
    Caraway Oil
    Cardamom Oil
    Carrot Seed Oil
    Catnip Oil
    Cedarwood Oil
    Chamomile Oil
    Cinnamon Oil
    Citronella Oil
    Clary-Sage Oil
    Clove Oil
    Coriander Oil
    Cypress Oil
    Dill Oil
    Eucalyptus Oil
    Fennel Oil
    Fir Needle Oil
    Frankincense Oil
    Geranium Oil
    German Chamomile Oil
    Ginger Oil
    Grapefruit Oil
    Helichrysum Oil
    Hyssop Oil
    Iris-Root Oil
    Jasmine Oil
    Juniper Oil
    Labdanum Oil
    Lavender Oil
    Lemon-Balm Oil
    Lemongrass Oil
    Lemon Oil
    Lime Oil
    Longleaf-Pine Oil
    Mandarin Oil
    Marjoram Oil
    Mimosa Oil
    Myrrh Oil
    Myrtle Oil
    Neroli Oil
    Niaouli Oil
    Nutmeg Oil
    Orange Oil
    Oregano Oil
    Palmarosa Oil
    Patchouli Oil
    Peppermint Oil
    Peru-Balsam Oil
    Petitgrain Oil
    Pine-Long Leaf Oil
    Pine-Needle Oil
    Pine-Swiss Oil
    Rosemary Oil
    Rose Oil
    Rosewood Oil
    Sage Oil
    Sandalwood Oil
    Savory Oil
    Spearmint Oil
    Spikenard Oil
    Swiss-Pine Oil
    Tangerine Oil
    Tea-Tree Oil
    Thyme Oil
    Vanilla Oil
    Verbena Oil
    Vetiver Oil
    Violet Oil
    White-Camphor Oil
    Yarrow Oil
    Ylang-Ylang Oil
    Aromatherapy
    Healing Baths For Colds
    Aromatherapy
    Herbal Cleansers
    Using Essential Oils


    AROMATHERAPY: HERBAL & CARRIER OILS DESCRIPTIONS & USES


    Almond, Sweet Oil
    Apricot Kernel Oil
    Argan Oil
    Arnica Oil
    Avocado Oil
    Baobab Oil
    Black Cumin Oil
    Black Currant Oil
    Black Seed Oil
    Borage Seed Oil
    Calendula Oil
    Camelina Oil
    Castor Oil
    Coconut Oil
    Comfrey Oil
    Evening Primrose Oil
    Flaxseed Oil
    Grapeseed Oil
    Hazelnut Oil
    Hemp Seed Oil
    Jojoba Oil
    Kukui Nut Oil
    Macadamia Nut Oil
    Meadowfoam Seed Oil
    Mullein Oil
    Neem Oil
    Olive Oil
    Palm Oil
    Plantain Oil
    Plum Kernel Oil
    Poke Root Oil
    Pomegranate Seed Oil
    Pumpkin Seed Oil
    Rosehip Seed Oil
    Safflower Oil
    Sea Buckthorn Oil
    Sesame Seed Oil
    Shea Nut Oil
    Soybean Oil
    St. Johns Wort Oil
    Sunflower Oil
    Tamanu Oil
    Vitamin E Oil
    Wheat Germ Oil





    HELPFUL RELATED MOONDRAGON NUTRITION BASICS LINKS

  • MoonDragon's Nutrition Basics Index
  • MoonDragon's Nutrition Basics: Amino Acids Index
  • MoonDragon's Nutrition Basics: Antioxidants Index
  • MoonDragon's Nutrition Basics: Enzymes Information
  • MoonDragon's Nutrition Basics: Herbs Index
  • MoonDragon's Nutrition Basics: Homeopathics Index
  • MoonDragon's Nutrition Basics: Hydrosols Index
  • MoonDragon's Nutrition Basics: Minerals Index
  • MoonDragon's Nutrition Basics: Mineral Introduction
  • MoonDragon's Nutrition Basics: Dietary & Cosmetic Supplements Index
  • MoonDragon's Nutrition Basics: Dietary Supplements Introduction
  • MoonDragon's Nutrition Basics: Specialty Supplements
  • MoonDragon's Nutrition Basics: Vitamins Index
  • MoonDragon's Nutrition Basics: Vitamins Introduction


  • NUTRITION BASICS ARTICLES

  • MoonDragon's Nutrition Basics: 4 Basic Nutrients
  • MoonDragon's Nutrition Basics: Avoid Foods That Contain Additives & Artificial Ingredients
  • MoonDragon's Nutrition Basics: Is Aspartame A Safe Sugar Substitute?
  • MoonDragon's Nutrition Basics: Guidelines For Selecting & Preparing Foods
  • MoonDragon's Nutrition Basics: Foods That Destroy
  • MoonDragon's Nutrition Basics: Foods That Heal
  • MoonDragon's Nutrition Basics: The Micronutrients: Vitamins & Minerals
  • MoonDragon's Nutrition Basics: Avoid Overcooking Your Foods
  • MoonDragon's Nutrition Basics: Phytochemicals
  • MoonDragon's Nutrition Basics: Increase Your Consumption of Raw Produce
  • MoonDragon's Nutrition Basics: Limit Your Use of Salt
  • MoonDragon's Nutrition Basics: Use Proper Cooking Utensils
  • MoonDragon's Nutrition Basics: Choosing The Best Water & Types of Water





  • RELATED MOONDRAGON HEALTH LINKS & INFORMATION

  • MoonDragon's Nutrition Information Index
  • MoonDragon's Nutritional Therapy Index
  • MoonDragon's Nutritional Analysis Index
  • MoonDragon's Nutritional Diet Index
  • MoonDragon's Nutritional Recipe Index
  • MoonDragon's Nutrition Therapy: Preparing Produce for Juicing
  • MoonDragon's Nutrition Information: Food Additives Index
  • MoonDragon's Nutrition Information: Food Safety Links
  • MoonDragon's Aromatherapy Index
  • MoonDragon's Aromatherapy Articles
  • MoonDragon's Aromatherapy For Back Pain
  • MoonDragon's Aromatherapy For Labor & Birth
  • MoonDragon's Aromatherapy Blending Chart
  • MoonDragon's Aromatherapy Essential Oil Details
  • MoonDragon's Aromatherapy Links
  • MoonDragon's Aromatherapy For Miscarriage
  • MoonDragon's Aromatherapy For Post Partum
  • MoonDragon's Aromatherapy For Childbearing
  • MoonDragon's Aromatherapy For Problems in Pregnancy & Birthing
  • MoonDragon's Aromatherapy Chart of Essential Oils #1
  • MoonDragon's Aromatherapy Chart of Essential Oils #2
  • MoonDragon's Aromatherapy Tips
  • MoonDragon's Aromatherapy Uses
  • MoonDragon's Alternative Health Index
  • MoonDragon's Alternative Health Information Overview
  • MoonDragon's Alternative Health Therapy Index
  • MoonDragon's Alternative Health: Touch & Movement Therapies Index
  • MoonDragon's Alternative Health Therapy: Touch & Movement: Aromatherapy
  • MoonDragon's Alternative Therapy: Touch & Movement - Massage Therapy
  • MoonDragon's Alternative Health: Therapeutic Massage
  • MoonDragon's Holistic Health Links Page 1
  • MoonDragon's Holistic Health Links Page 2
  • MoonDragon's Health & Wellness: Nutrition Basics Index
  • MoonDragon's Health & Wellness: Therapy Index
  • MoonDragon's Health & Wellness: Massage Therapy
  • MoonDragon's Health & Wellness: Hydrotherapy
  • MoonDragon's Health & Wellness: Pain Control Therapy
  • MoonDragon's Health & Wellness: Relaxation Therapy
  • MoonDragon's Health & Wellness: Steam Inhalation Therapy
  • MoonDragon's Health & Wellness: Therapy - Herbal Oils Index







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