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MoonDragon's Health & Wellness
Disorders

ALUMINUM TOXICITY


"For Informational Use Only"
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  • Aluminum Toxicity Description
  • Aluminum Toxicity Signs & Symptoms
  • Aluminum Toxicity Causes
  • Aluminum Toxicity Conventional Medical Treatment Considerations
  • Aluminum Toxicity Diet & Nutrition Recommendations
  • Aluminum Toxicity Nutritional Supplement Recommendations
  • Aluminum Toxicity Notify Health Care Provider
  • Aluminum Toxicity Supplements & Products




  • ALUMINUM TOXICITY DESCRIPTION

    ALUMINUM ACCUMULATION

    Aluminum is not a heavy metal, but it can be toxic if present in excessive amounts. Even in small amounts, aluminum can be toxic if deposited in the brain. Aluminum is thought to play a major role in most of the neurodenerative diseases and has been a suspect in Alzheimer's for many years as well as in the development of dementia, Parkinson's, Lou Gehrig's disease (ALS) and other degenerative diseases.

    Experimental studies show that aluminum can produce all the same changes in the brain we see with Alzheimer’s disease. Many of the symptoms of aluminum toxicity are similar to those of Alzheimer's disease and osteoporosis. Aluminum toxicity can lead to colic, rickets, gastrointestinal disturbances, poor calcium metabolism, extreme nervousness, anemia, headaches, decreased liver and kidney function, forgetfulness, speech disturbances, memory loss, softening of the bones, and weak, aching muscles.

    Most of us are exposed to dietary sources of aluminum including cookware, medications, baking powder, vaccinations, several foods (such as teas) and public drinking water. Normally, people absorb very littel of ingested aluminum, but recent studies have discovered that those with Down's syndrome and Alzheimer's disease absorb a lot more aluminum than normal. n fact, Down’s children absorb 11 times more aluminum than is normally absorbed. Children with Down’s syndrome have the same pathological changes in their brains as those with Alzheimer’s disease. Ironically, several commonly consumed products dramatically increase the absorption of aluminum and increase its toxicity in the brain.

    Because aluminum is excreted through the kidneys, toxic amounts of aluminum may impair kidney function. The accumulation of aluminum salts in the brain has bee implicated in seizures and reduced mental faculties. To reach the brain, aluminum must pass the blood-brain barrier, an elaborate structure that filters the blood before it reaches this vital organ. Elemental aluminum does not readily pass through this barrier, but certain aluminum compounds, such as aluminum fluoride, do. Many municipal water supplies are treated with both alum (aluminum sulfate) and fluoride, and these two chemicals readily combine with each other in the blood. Fluoride, when combined with even small amounts of aluminum, produces dramatic destruction of the same brain cells that are destroyed in Alzheimer's disease. In fact, as little as 0.5 ppm (parts per million) fluoride added to aluminum in water was found to produce extensive brain cell loss in the hippocampus, the memory part of the brain. Most water systems add 1 to 1.5 ppm fluoride and all add aluminum. Moreover, aluminum fluoride, once formed, is very poorly excreted in the urine.

    The amino acid glutamate, as found in monosodium glutamate (MSG), also increases aluminum absorption and deposition in the brain. MSG is added to most processed foods, usually under a disguised name such as hydrolyzed protein, soy extract, natural flavoring or even spices. As with fluoride, glutamate is even more destructive to brain cells when combined with aluminum.

    Another surprising culprit is citric acid. Lemon juice is high in citric acid, as are most citrus fruits. Adding lemon to tea, for example, increases aluminum absorption from the tea (which contains very high aluminum levels) over sevenfold. This is why you should not add lemon to your tea.

    Intestinal absorption of high levels of aluminum and silicon can result in the formation of compounds that accumulate in the cerebral cortex and prevent nerve impulses from being carried to and from the brain in the proper manner. Chronic calcium deficiency can aggravate the situation. People who have worked in aluminum smelting plants for long periods have been known to experience dizziness, impaired coordination, and a loss of balance and energy. The accumulation of aluminum in the brain has been cited as a possible cause for these symptoms. Perhaps the most alarming, there is evidence to suggest that long-term accumulation of aluminum in the brain may contribute to the development of Alzheimer's disease.

    MoonDragon's Health & Wellness: Aluminum & Alzheimer's Connection





    ALUMINUM TOXICITY FREQUENT SIGNS & SYMPTOMS

    ALUMINUM ACCUMULATION SYMPTOMS

  • Symptoms similar to osteoporosis.
  • Symptoms similar to Alzheimer's disease.
  • Speech disturbances.
  • Weak, aching muscles.
  • Impaired coordination.
  • Fatigue, tiredness, loss of energy.
  • Memory loss, forgetfulness.
  • Anemia.
  • Colic and gastrointestinal disturbances.
  • Rickets and softening of the bones.
  • Poor calcium metabolism.
  • Extreme nervousness.
  • Headaches, mild to severe.
  • Dizziness. Loss of Balance.
  • Impaired kidney function.
  • Impaired liver function.





  • ALUMINUM TOXICITY CAUSES

    ALUMINUM SOURCES

    It has been estimated that the average person ingests between 3 and 10 milligrams of aluminum a day. Aluminum is the most abundant metallic element in the earth's crust. Aluminum is absorbed into the body primarily through the digestive tract, but also through the lungs and skin, and is absorbed by and accumulates in body tissues. Because aluminum permeates our air, water, and soil, it is found naturally in varying amounts in nearly all food and water. Some sources of Aluminum include:

  • Aluminum cookware, cooking utensils, and aluminum foil.
  • Over-the-counter pain killers.
  • Anti-inflammatories.
  • Douche preparations.
  • An additive to baking powder.
  • Used in food processing.
  • Antiperspirants.
  • Toothpaste.
  • Dental amalgams.
  • Bleached flour.
  • Grated cheese.
  • Table salt.
  • Beer, especially when packaged in aluminum cans.
  • City or town water supplies are a prominent source of aluminum.
  • Antacids.

  • Excessive use of antacids is probably the most common cause of aluminum toxicity in this country, especially in people who have kidney problems. Many over-the-counter antacids contain amounts of aluminum hydroxide that may be too much for the kidneys to excrete successfully. Even antacids that contain a mixture of aluminum and other ingredients may pose a problem; in some people, such products may cause the same reaction as products composed entirely of aluminum compounds.

    ALUMINUM CONCENTRATIONS &: ABSORPTION

    Aluminum is a trivalent cation found in its ionic form in most kinds of animal and plant tissues and in natural waters everywhere. It is the third most prevalent element and the most abundant metal in the earth's crust, representing approximately 8 percent of total mineral components. Due to its reactivity, aluminum in nature is found only in combination with other elements.

    Dietary aluminum is ubiquitous but in such small quantities that it is not a significant source of concern in persons with normal elimination capacity. Urban water supplies may contain a greater concentration because water is usually treated with aluminum before becoming part of the supply. Subsequent purification processes that remove organic compounds take away many of the same compounds that bind the element in its free state, further increasing aluminum concentration.

    All metals can cause disease through excess. In addition, essential metals can affect the human body in the case of deficiency or imbalance. Malabsorption through diarrheal states can result in essential metal and trace element deficiencies. Toxic effects are dependent upon the amount of metal ingested, entry rate, tissue distribution, concentration achieved, and excretion rate. Mechanisms of toxicity include inhibition of enzyme activity and protein synthesis, alterations in nucleic acid function, and changes in cell membrane permeability.

    No known physiologic need exists for aluminum; however, because of its atomic size and electric charge (0.051 nm and 3+, respectively), it is sometimes a competitive inhibitor of several essential elements with similar characteristics, such as magnesium (0.066 nm, 2+), calcium (0.099 nm, 2+), and iron (0.064 nm, 3+). At physiological pH, aluminum forms a barely soluble Al(OH)3 that can be easily dissolved by minor changes in the acidity of the media.

    Approximately 95 percent of an aluminum load becomes bound to transferrin and albumin intravascularly and is then eliminated renally. In healthy subjects, only 0.3 percent of orally administered aluminum is absorbed via the GI tract, and the kidneys effectively eliminate aluminum from the human body. Only when the GI barrier is bypassed, such as by intravenous infusion or in the presence of advanced renal dysfunction, does aluminum have the potential to accumulate. As an example, with intravenously infused aluminum, 40 percent is retained in adults and up to 75 percent is retained in neonates. Parathyroid hormone may increase intestinal absorption of aluminum.

    Aluminum is absorbed from the GI tract in the form of oral phosphate-binding agents (aluminum hydroxide), parenterally via immunizations, via dialysate on patients on dialysis or total parenteral nutrition (TPN) contamination, via the urinary mucosa through bladder irrigation, and transdermally in antiperspirants. Lactate, citrate, and ascorbate all facilitate GI absorption. If a significant aluminum load exceeds the body's excretory capacity, the excess is deposited in various tissues, including bone, brain, liver, heart, spleen, and muscle. This accumulation causes morbidity and mortality through various mechanisms.

    PATHOPHYSIOLOGY

    Aluminum toxicity is usually found in patients with impaired renal function. Acute intoxication is extremely rare; however, in persons in whom aluminum clearance is impaired, it can be a significant source of pathology. Aluminum toxicity was originally described in the mid-to-late 1970s in a series of patients in Newcastle, England, through an associated osteomalacic dialysis osteodystrophy that appeared to reverse itself upon changing of the dialysate water to deionized water (ie, aluminum-depleted water).

    Previously, the only known dialysis-associated bone disease was osteitis fibrosa cystica, which was the result of abnormalities in vitamin D production that resulted in a secondary hyperparathyroidism, increased bone turnover, and subsequent peritrabecular fibrosis. In aluminum-related bone disease, the predominant features are defective mineralization and osteomalacia that result from excessive deposits at the site of osteoid mineralization, where calcium would normally be placed.

    Since the role of aluminum in disease has been identified, more attention has been paid to the element, leading to its recognition in several other processes. For example, among patients with osteomalacia, there has been a closely associated dialysis encephalopathy, which is thought to be caused by aluminum deposition in the brain. Aluminum brain concentrations should be lower than 2 µg/g. A 10-fold increase in aluminum concentrations was reported in patients with aluminum intoxication through the use of hemodialysis solutions with high levels of aluminum.

    Aluminum causes an oxidative stress within brain tissue. Since the elimination half-life of aluminum from the human brain is 7 years, this can result in cumulative damage via the element's interference with neurofilament axonal transport and neurofilament assembly. Some experts believe it plays a role in leading to the formation of Alzheimer-like neurofibrillary tangles. It is suggested that the heterogeneous symptoms of autism spectrum disorders have a connection with dysregulation of glutamatergic neurotransmission in the brain along with enhancement of excitatory receptor function by proinflammatory immune cytokines as the underlying pathophysiological process.

    In this regard, dietary excitotoxins including aluminum can exacerbate the clinical presentation by worsening of excitotoxicity and by microglial priming. This opens the discussion to the use of nutritional factors that reduce excitotoxicity and brain inflammation as a maneuver to alleviate neurotoxic effects of aluminum. The central nervous system appears to be extremely sensitive to metal-induced oxidative stress. High aluminum concentrations have been found in postmortem brain specimens of patients with Parkinson's disease and on animals models where administration of aluminum caused a strong decrease in dopamine content of the striatum.

    Aluminum also has a direct effect on hematopoiesis. Excess aluminum has been shown to induce microcytic anemia. Daily injections of aluminum into rabbits produced severe anemia within 2 to 3 weeks. The findings were very similar to those found in patients suffering from lead poisoning.

    Aluminum may cause anemia through decreased heme synthesis, decreased globulin synthesis, and increased hemolysis. Aluminum may also have a direct effect on iron metabolism: it influences absorption of iron via the intestine, it hinders iron's transport in the serum, and it displaces iron's binding to transferrin. Patients with anemia from aluminum toxicity often have increased reticulocyte counts, decreased mean corpuscular volume, and mean corpuscular hemoglobin.

    Other organic manifestations of aluminum intoxication have been proposed, such as a slightly poorer immunologic response to infection, but the mechanism by which it exerts its effect is complex and multifactorial. It has also been linked to vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome, thus highlighting the potential dangers associated with aluminum-containing adjuvants as described recently.

    FREQUENCY OF OCCURANCE IN THE UNITED STATES

    The actual incidence of aluminum toxicity is unknown. The greatest incidence is observed in patients with any degree of renal insufficiency. A higher incidence is observed in populations who have aluminum-contaminated dialysate or who are taking daily oral phosphate-binding agents. Patients who require long-term TPN are at increased risk as well.

    The potential for aluminum toxicity caused by parenteral nutrition in patients (n=36; age 50.4±20.4 y, weight 90.2±32.8 kg) who have risk factors of both acute kidney injury and parenteral nutrition support. Aluminum exposure was determined for each patient by multiplying the volume of each parenteral nutrition component by its concentration of aluminum. The initial serum urea nitrogen and serum creatinine levels were 47±23 and 3.3 ± 1.4 mg/dL, respectively. Twelve patients received supportive dialysis. The mean aluminum exposure was 3.8±2 µg/kg/day in the 36 patients; the majority of patients, 29 out of 36, had safe calculated aluminum exposure (< 5 µg/kg/d), and 7 had high calculated aluminum exposure (>5 µg/kg/d). Patients with high aluminum exposure received more aluminum from calcium gluconate compared with those who had safe aluminum exposure (357±182 vs 250±56 µg/d).

    It was concluded using calculations that most patients with acute kidney injury who require parenteral nutrition do not receive excessive exposure to aluminum from the parenteral nutrition formulation. The limitation of the study was its retrospective design, which resulted in calculated versus direct measurement of aluminum.

    Animal studies in rats and case reports have implicated the use of oral aluminum-containing antacids during pregnancy as a possible cause for abnormal fetal neurologic development.

    Potential additional sources of increased chances for contamination are as follows:
    1. A role for fatty acids common in food as factors that lead to an increase of the paracellular absorption of aluminum.
    2. Advances in nanotechnology have led to the exposure of humans to engineered aluminum nanomaterials (NMs) that could potentially induce genomic changes. (By using a rat model, it was found that Al2O3 NMs were able to induce size- and dose-dependent genotoxicity in vivo.
    3. Intravesical irrigation with aluminum for hemorrhagic cystitis, a life-threatening complication that might occur in bone marrow transplantation, chemotherapy, and radiotherapy, as described in a pediatric patient.

    INTERNATIONAL INCIDENCE

    Some evidence suggests that, in developing countries where contaminated dialysis water is still used, aluminum-related disease is more prevalent. Also, as people still use over-the-counter aluminum-containing phosphate binders, aluminum deposition within the bone will continue and serve as a reservoir for continued exposure because of its long elimination half-life.

    MORTALITY & MORBIDITY RATES

    The mortality rate may be as high as 100 percent in patients in whom the condition goes unrecognized. Today, however, recognition by nephrologists is the norm, and increased awareness by all practitioners has led to earlier detection and overall avoidance of the syndrome. Morbidity and mortality have been diminished significantly. Prior to this, bone pain, multiple fractures, proximal myopathy, and the sequelae of dementia have been the main sources of morbidity.

    Race: Aluminum toxicity has no predilection for any race.
    Sex: Aluminum toxicity has no predilection for either sex.
    Age: Aluminum toxicity is observed in all age groups, but its end-organ effects are more prevalent in elderly persons, who may have diminished renal function.





    ALUMINUM TOXICITY TREATMENT CONSIDERATIONS

    CONVENTIONAL MEDICAL DIAGNOSIS & THERAPY

    MEDICAL HISTORY

    The signs and symptoms of aluminum toxicity are usually nonspecific. In patients on long-term hemodialysis, osteomalacia is associated with the accumulation of aluminum in bone. Most evidence to support skeletal toxicity is from animal studies. Studies have also shown that patients on hemodialysis who are exposed to dialysate containing high aluminum concentrations are at increased risk of osteomalacia. Some of the clinical symptoms of the disease entity reflect the chief complaint. An emergency health care practitioner will rarely consider aluminum toxicity as a possible diagnosis in a patient on dialysis who presents with an acute mental status change; however, these patients are the specific group most closely associated with the syndrome. Typical presentations may include proximal muscle weakness, bone pain, multiple nonhealing fractures, acute or subacute alteration in mental status, and premature osteoporosis. These patients almost always have some degree of renal disease. Most patients are on hemodialysis or peritoneal dialysis. When obtaining the history, the patient should be asked specifically about the supplemental use of oral aluminum hydroxide, particularly if the patient does not undergo dialysis. In children, special awareness must be made in those who require parenteral nutrition so as not to give excessive amounts of aluminum in the TPN.

    PHYSICAL FINDINGS

    Unfortunately, physical findings are often noticeably lacking in patients with aluminum toxicity, and findings usually mimic other disease processes. Patients can present with multiple fractures (particularly of the ribs and pelvis), proximal muscle weakness, mutism, seizures, and dementia. Some studies have shown a direct correlation between aluminum levels and intensity of uremic pruritus. In children, bony deformity is more commonly due to the increased rate of growth and remodeling. Children may also express varying degrees of growth retardation. The areas of deformity in children usually involve the epiphyseal plates (ie, femur, wrist). In adults, thoracic cage abnormalities, lumbar scoliosis, and kyphosis can be present.

    Toxic effects are dependent upon the amount of metal ingested, entry rate, tissue distribution, concentration achieved, and excretion rate. Mechanisms of toxicity include inhibition of enzyme activity and protein synthesis, alterations in nucleic acid function, and changes in cell membrane permeability. Aluminum toxicity is usually found in patients with renal impairment. Acute intoxication is extremely rare; however, in persons in whom aluminum clearance is impaired, it can be a source of significant toxicity.

    DIAGNOSTIC CONSIDERATIONS

    A broad differential exists for each potential problem, depending upon the presenting complaint (e.g., musculskeletal trauma, altered mental status, anemia).

  • Brain Abscess
  • Cryptococcosis
  • Cysticercosis
  • Delirium
  • Delirium Tremens
  • Depression
  • Eastern Equine Encephalitis
  • Encephalopathy, Dialysis
  • Encephalopathy, Hepatic
  • Encephalopathy, Hypertensive
  • Encephalopathy, Uremic
  • Ependymoma
  • Gliobastoma Multiforme
  • Head Trauma
  • Hemolytic-Uremic Syndrome
  • Hepatorenal Syndrome
  • Hyperosmolar Coma
  • Hyperparathyroidism
  • Hyperphosphatemia
  • Hypocalcemia
  • Hypoglycemia
  • Hypothermia
  • Hypothyroidism

  • LABORATORY STUDIES

    Generally, findings from an aluminum level blood test are unreliable, as most of the body's stores are bound in bone and tissue and are not reflected in the serum value. A deferoxamine infusion test can be performed but may take more than 48 hours to yield a result. Deferoxamine liberates aluminum from tissues by chelating it and leads to an increased serum level compared with one taken prior to infusion. The combination of a baseline immunoreactive parathyroid hormone level of less than 200 mEq/mL and a change in serum aluminum value of 200 ng/mL after deferoxamine is 90 percent specific and has a positive predictive value of 85 percent for aluminum toxicity.

    Aluminum excess has a direct effect on hematopoiesis and has been shown to induce anemia. Findings on peripheral smears in patients with aluminum toxicity include microcytic anemia (hypochromic, normochromic), anisocytosis, poikilocytosis, chromophilic cells, and basophilic stippling. Note that these are the same findings observed in patients with lead poisoning. Aluminum can also be found in bone marrow macrophages.

    IMAGING STUDIES

    In radiographs, Looser zones (ie, lines of radiolucency parallel to the plane of growth in long bones) may be observed in severe cases, although they are more common with other causes of adult osteomalacia. Pathological fractures may also be observed. Bone scintigraphy shows a characteristic pattern in aluminum toxicity.

    BONE BIOPSY

    Bone biopsy from the iliac crest is frequently performed to determine the etiology of bone disease in patients on dialysis because renal osteodystrophy can be multifactorial (e.g., osteomalacia, uremic bone disease, hyperparathyroidism, aluminum deposition). Histochemical staining for aluminum and determination of osteoid volume, bone turnover rate, and osteoblast/clast cell count are some of the methods used for subtyping the bone disease.

    PROCEDURES

    Very few procedures are involved in the diagnosis of aluminum-related illness. Bone marrow biopsy is performed to distinguish between aluminum osteodystrophy and other causes of osteomalacia.

    Hair analysis can be used to determine levels of aluminum in the body.

    HISTOLOGIC FINDINGS

    Histologic findings in aluminum-relalted osteomalacia reflect the decrease in mineralization of newly formed bone matrix.
    • An increase in the surface covered by osteoid occurs, as does an increase in the osteoid seams.
    • Osteoid volume and thickness also increase.
    • In histologic sections stained with eosin, the areas of greater mineralization tend to appear violet or blue, whereas the osteoid seams appear pink.

    CHELATION THERAPY & AWARENESS

  • If you use chelation therapy, use oral chelating agents only. Many researchers believe that aluminum cannot be chelated out of the body as some heavy metals can, but that it can be displaced or moved.

  • Some research indicates that the longer you cook food in aluminum pots, the more they corrode, and the more aluminum compounds migrate into food and are absorbed by the body. Aluminum is more readily dissolved by acid-forming foods, such as coffee, cheeses, meats, black and green tea, cabbage, cucumbers, tomatoes, turnips, spinach, and radishes.

  • Acid rain leeches aluminum out of the soil and into drinking water.

  • MoonDragon's Health & Wellness: Alzheimer's Disease

    CHELATION THERAPY - MEDICAL MANAGEMENT

    The most important part of emergency medical treatment is the recognition of possible aluminum toxicity based on risks (eg, renal insufficiency, aluminum exposure) and symptoms (eg, altered mental status, anemia, osteoporosis). Treatment of aluminum toxicity includes elimination of aluminum from the diet, TPN, dialysate, medications, antiperspirants, and an attempt at the elimination and chelation of the element from the body's stores. Avoidance of aluminum is easily achieved once the need to do so is recognized.

    Elimination is accomplished through the administration of deferoxamine through any of several routes.
    • Serum aluminum level greater than 50 to 60 µg/L (mcg/dL) suggests aluminum overload, may correlate with toxicity, and can be used as an indication to start chelation therapy in symptomatic patients.

    • Symptomatic patients with lower serum aluminum levels (eg, greater than 20 mcg/dL) may require chelation therapy.

    • A low dose of deferoxamine therapy (2.5 mg/kg/wk) is therapeutically effective as standard dose (5 mg/kg/wk) for the treatment of aluminum overload.

    Chelation therapy with deferoxamine should be initiated in consultation with a nephrologist and a medical toxicologist, and this can be performed upon admission.
    • Deferoxamine, the metal-free ligand of the iron-chelate isolated from the bacterium Streptomyces pilosus, is used for acute and chronic iron toxicity and aluminum toxicity.
    • It has a high affinity for ferric iron and does not affect iron in hemoglobin or cytochromes.

    No surgical care is applicable to this disorder. Hemodialysis is performed in conjunction with deferoxamine as therapy for whole-body chelation. Usually, a nephrologist is already a part of the patient's medical team. If not, one should be consulted early in the course. A hematologist and a neurologist may be able to assist with the patient's care. The goals of pharmacotherapy are to reduce morbidity and to prevent complications

    Since dietary aluminum is ubiquitous, no specific dietary guidelines are available for its avoidance. Special diets should be maintained for specific associated disease entities (eg, diabetes, renal failure). Activity modification may not be necessary unless the patient is at risk for frequent falls. If this is the case, a home attendant or family member should assist the patient with daily living activities.

    METAL CHELATORS

    These agents bind free metal and do not chelate other trace metals of nutritional importance. Metals are excreted in the urine and bile.

  • Deferoxamine (Desferal mesylate): Metal-free ligand of the iron chelate isolated from the bacterium S pilosus. Used for acute and chronic iron toxicity as well as aluminum toxicity and has a high affinity for ferric iron. Does not affect iron in cytochromes or hemoglobin. PO/IM administration not established. Several case reports and cohorts using varying doses indicate effectiveness when administered IV.

    FOLLOWUP - FURTHER PATIENT CARE

    Start chelation therapy in symptomatic patients with elevated serum aluminum level in consultation with a nephrologist and a medical toxicologist. Use clinical symptoms and serum aluminum levels as indicators of therapeutic success. Reduce exposure to aluminum-containing products. If chelation therapy and hemodialysis/peritoneal dialysis are not able to be provided, transfer the patient to an institution with a higher level of care.

    PROGNOSIS

    Depending upon the degree of dementia and overall medical frailty of the patient, most improve with deferoxamine therapy. Some patients, however, succumb to their underlying disease processes before any noticeable improvement in mental status or anemia occurs. Whether aluminum toxicity itself is fatal is unknown. Typically, patients' underlying diseases and medical frailty lead to early morbidity and mortality.

    PATIENT EDUCATION

    Educate pregnant and breastfeeding females, and any patient with compromised renal function, about the potential dangers associated with the use and overuse of aluminum-containing antacids. A safe alternative includes Calcium Carbonate, such as found in Tums.

    Educate patients to refrain from driving or operating hazardous machinery if they develop dizziness or impaired vision or hearing during treatment.

    ALTERNATIVE WAYS TO REMOVE ALUMINUM FROM THE BODY

    Chemicals that remove toxic metals from the tissues and organs of the body do so by a process called chelation, hence they are called chelators. One of the most effective chelators for removing aluminum from the brain is the experimental drug Feralex-G. One advantage of this drug is that it can be taken by mouth rather than injected. When combined with Ascorbate (vitamin C), it was shown to produce excellent reductions in brain aluminum levels. Unfortunately, the drug is not yet available.

    A study done in 1993 at the University of Toronto found that patients given aluminum-chelating drugs deteriorated at half the rate of those given no treatment. Recent studies have found that using aluminum chelation could reverse the pathological changes characteristic of Alzheimer’s dementia.

    SUPPLEMENT THERAPY

    Until the new oral chelating drug is ready for market you may want to reduce your brain load of aluminum by using the following supplements, also shown to significantly lower brain aluminum.

  • Magnesum Citramate. Take 500 mg three times a day. Magnesium reduces brain levels of mercury and the citramate, a combination of citrate and malate, has been shown to significantly stimulate elimination of aluminum from the body. In this combination the supplements are even more effective.

  • Ascorbate (Magnesium Ascorbate or Calcium Ascorbate). Take 1,500 mg three times a day on an empty stomach. A recent study found ascorbate to be a very effective chelator of aluminum, especially when the aluminum was bound to brain cell DNA. Taking higher doses of ascorbate with the Magnesium Citramate increased the removal of aluminum even more. This has been referred to as molecular shuttle chelation.

  • Malate. Take two 500 mg capsules three times a day on an empty stomach for one month, then two capsules a day thereafter. Malate was shown to be one of the more effective aluminum chelators for the brain.

  • Pyruvate (Calcium Pyruvate). Take 500 mg with each meal to remove the aluminum from your food. Pyruvate has been shown to effectively prevent aluminum absorption.

  • Flavonoids. Eat a lot of fresh vegetables. Supplements containing flavonoids, such as Quercetin and Hesperidin, also prevent aluminum absorption.

  • Chlorella helps remove mercury and lead and may remove aluminum.


  • These supplements are in addition to the Antioxidant Vitamins you normally take.





    ALUMINUM TOXICITY DIET & NUTRITION RECOMMENDATIONS

    DIET & FOOD PREPARATION

    You can reduce your brain load of aluminum yourself by using the following supplements, also shown to significantly lower brain aluminum.

  • Magnesum Citramate Magnesium reduces brain levels of mercury and the citramate, a combination of citrate and malate, has been shown to significantly stimulate elimination of aluminum from the body.
  • Ascorbate (as magnesium or Calcium Ascorbate). A study found ascorbate to be a very effective chelator of aluminum, especially when the aluminum was bound to brain cell DNA. Taking higher doses of ascorbate with the Magnesum Citramate increased the removal of aluminum even more.
  • Malate. Malate was shown to be one of the more effective aluminum chelators for the brain.
  • Pyruvate (as Calcium Pyruvate). Pyruvate has been shown to effectively prevent aluminum absorption.
  • Flavonoids. Eat a lot of fresh vegetables. Supplements containing flavonoids, such as Quercetin and Hesperidin, also prevent aluminum absorption.
  • Chlorella helps remove mercury and lead and may remove aluminum. These supplements are in addition to the antioxidant vitamins you normally take.
  • Eat a diet that is high in Fiber and includes Apple Pectin.
  • Use only stainless steel, glass, or iron cookware. Stainless steel is best.
  • Beware of products containing aluminum. Read labels and avoid those that contain aluminum, or dihydroaluminum. See MoonDragon's Health & Wellness: Aluminum & Alzheimer's Connection for more suggestions.

  • Most individuals with Alzheimer's disease have low levels of Vitamin C, and the Beta Carotene, Vitamin B-1, Vitamin B-6, Folate and Vitamin B-12. The latter three are particularly important, since they regulate a special series of metabolic steps in brain cells necessary for forming neurotransmitter chemicals and repairing DNA. When these nutrients are deficient, a special chemical called homocysteine accumulates.

    Recent studies have found that a large number of Alzheimer's disease patients have elevated homocysteine levels. Besides being a sign of impaired metabolism, homocysteine is in a class of special brain cell toxins called excitotoxins. These toxins literally excite certain brain cells to death. They are considered a central mechanism in all of the neurodegenerative diseases, such as Alzheimer's dementia and Parkinson's disease. Excitotoxins generate large numbers of free radicals in brain cells and brain cell connections (synapses). Vitamin E and Vitamin C, and the Carotenoids and special antioxidants from plants called flavonoids all act together to protect the brain from free radicals and, hence, excitotoxicity.

    Several studies have shown that increasing these Antioxidants in the diet slows the course of Alzheimer's disease and Parkinson's disease and may prevent the disease in some cells we see destroyed in Alzheimer's disease.

    Numerous studies have shown that chronic activation of the brain’s immune system is closely connected to this terrifying disorder. Many of these studies also have shown that the greatest risk is among those with impaired immunity. We know that as we age, the immune system becomes impaired, primarily because of poor nutrition. In fact, several studies have shown that aged-related immune problems can be corrected with nutrients such as Selenium, Vitamin E and Vitamin C, and the Carotenoids. Of even greater importance is the finding that Vitamin D-3 plays a major role in preventing overreaction of the immune system, as seen in these diseases. While part of the immune system is impaired, another part is overactive. This imbalance causes the problem. Nutrition can re-establish the proper immune balance.

    REDUCING YOUR RISK WITH DIET

  • Watch Your Diet: Most important is your diet. You should eat low-fat foods, at least five servings of fruits and vegetables (primarily vegetables) and no more than a slice of whole grain bread a day, along with a minimum of high-glycemic carbohydrates, and drink filtered fluoride-free water. Carbohydrates are classified as to how fast they are absorbed and converted to simple sugars. Those easily converted and absorbed are considered high-glycemic; others are called low-glycemic carbohydrates. The best diet is the Mediterranean diet, which is higher in protein (mainly fish), high in vegetables and extra virgin Olive Oil, and low in carbohydrates.

  • Seafoods can be high in mercury (methylmercury), so caution must be exercised. It is best to get your Omega-3 Oils from supplements. Omega-3 oils are composed of two components, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). DHA is the most important for protecting and nurturing the brain. In one study, those who consumed omega-3 fatty acid–containing foods once a week or more had a 60 percent reduction in Alzheimer’s disease. Interestingly, DHA has been shown to powerfully protect the brain from excitotoxins. The EPA component had little effect. Pure DHA can be obtained from most health supplement suppliers. Another source of omega-3 fatty acids is from special eggs that contain high amounts of this beneficial fat. The highest contents are found in Christopher Eggs. The chickens producing these eggs are fed a special diet high in omega-3 fatty acids, which then enters the egg yolks. A single egg supplies 600 mg of omega-3 fatty acids.

  • Fruits and especially vegetables contain some of the most powerful chemical antioxidants found naturally. They also contain powerful anti-excitotoxic, anti-inflammatory, immune-modulating and antiviral components as well. Eating at least five servings of vegetables a day also plays a major role in preventing these neurodegenerative diseases. A recent study found that of 1,367 people over age 65 followed for five years, those with the highest intake of flavonoids from fruits and vegetables had a 51 percent lower incidence of Alzheimer's disease.

  • Of particular interest has been Blueberry extract. In one study, it was found not only to slow the aging of the brain but also to reverse some of the aging changes. A more recent study found that blueberry extract could completely prevent Alzheimer's disease in a hereditary animal model of the disease. This means that blueberry extract might prevent the disease even in those inheriting both of the APOE4 genes. It is important to appreciate that these experiments were done using blueberry extracts and not whole blueberries. The extracts contain much higher concentrations of the blueberry flavonoids than found in a bowl of blueberries.

  • One of the hottest areas of research has been brain protection through caloric reduction by fasting. It has been known for almost half a century that animals placed on low-calorie diets live significantly longer than those on regular or, especially, high-calorie diets. As we have seen, high-calorie intake is especially harmful to the brain. Previously, it was assumed that reducing calories reduces the number of free radicals produced by cells, which it does. Research found that it greatly increased the concentration of two brain-protecting chemicals called nerve growth factor and telomerase. These two chemicals can protect the brain’s cells against the beta-amyloid of Alzheimer's disease, strengthen synapses and protect against excitotoxicity. In other words, they can protect against all the processes seen in Alzheimer's disease. The best results were found with fasting one day a week. Weekly fasting also helped correct insulin excess, something also connected with these diseases.

  • Take Antioxidants. While you should increase your intake of all of the antioxidant vitamins, including Vitamin C, Vitamin D, Vitamin E, Vitamin K, Carotenoids and all the B Vitamins, you also should supplement with additional Antioxidants. Some of the more powerful are the Flavonoids, special components isolated from plants. These include Hesperidin, Quercetin, Green Tea extract, Artichoke extract, Grape Seed extract and Bilberry, all available from natural supplement suppliers.

  • One supplement found to provide major protection to the brain is Melatonin. Most people think of it as nothing more than a sleep aid. In fact, it is one of the brain’s most important antioxidants and actually increases the antioxidant enzyme content of the brain. This is especially important because recent studies have shown that these antioxidant enzymes are low in people who develop Alzheimer's dementia and Parkinson's disease. With aging, the amount of melatonin begins to decline, one of the reasons for the high frequency of insomnia in the elderly. If you notice you no longer dream, your melatonin levels are probably low. Low levels are rarely seen below age 45.

  • All cells contain a very powerful antioxidant called Glutathione. It is especially important for protecting the brain, especially against excitotoxicity and mercury poisoning. Low levels of this antioxidant are seen in all cases of neurodegenerative disease, including Alzheimer's and Parkinson's. Ironically, it is fairly easy to increase the levels of glutathione in all your cells.

  • The supplement N-acetyl-L cysteine (NAC) has been shown to dramatically increase Glutathione levels. Magnesium, Vitamin C, Alpha-Lipoic Acid and a high intake of vegetables also increase glutathione levels. An additional benefit is that high glutathione levels also help prevent cancer. A high intake of MSG and other excitotoxins dramatically lowers brain glutathione levels.


  • NUTRITIONAL SUPPLEMENTS

    Unless otherwise specified, the dosages recommended here are for adults. For a child between ages 12 and 17, reduce the dose to 3/4 the recommended amount. For a child between 6 and 12, use 1/2 the recommended dose.

    NUTRIENTS
    Supplement
    Suggested Dosage
    Comments
    Very Important
    Apple Pectin
    2 Tablespoons twice daily. Binds with metals in the colon and excretes them from the body.


    Apple Pectin is a fiber that may be beneficial for cholesterol levels, arteriosclerosis (hardening of the arteries), diabetes, and may inhibit cancer metastases. Supporting sound intestinal health is essential to every lifestyle, Apple Pectin is a completely natural water-soluble fiber that gels-up when mixed with water, offering digestive support that is natural and simple. As a dietary fiber, Apple Pectin can be a smart alternative to help promote desired intestinal health without the use of chemicals.

  • Apple Pectin Fiber Herbal Products
  • Calcium
    1,500 mg daily. Minerals that bind with aluminum and eliminate it from the body. Use chelate form.


  • Calcium Supplement Products
  • Magnesium
    750 mg daily. Minerals that bind with aluminum and eliminate it from the body. Use chelate form.


  • Magnesium Supplement Products
  • Coenzyme A
    As directed on label. Facilitates the repair of RNA and DNA. Supports the immune system's detoxification of many dangerous substances. Can streamline metabolism, ease depression and fatigue, and increase energy. Works well with CoQ10.


  • Coenzyme A Supplement Products
  • Garlic (Kyolic)
    2 capsules 3 times daily. Acts as a detoxifier.


  • Garlic & Kyolic Garlic Herbal Products
  • Kelp
    2,000 to 3,000 mg daily. Has a balanced mineral content. Acts as a detoxifier of excess metals.


    Kelp is a large, leafy brown algae is high in nutrition, especially minerals. Kelp is a good source of marine minerals, including potassium, magnesium, calcium and iron. It is also an excellent source of natural iodine. Due to overwhelming research results, Kelp has become an effective treatment for thyroid disorders and treating thyroid and mineral deficiencies, obesity, adrenal deficiencies, energy and endocrine gland disorders. Aids in the function of both the pituitary and adrenal glands, promoting glandular health. It regulates metabolism to help digest food. Helps to rid the body of toxins. Kelp is an alternative, diuretic, hypotensive, and antibiotic and also contains vitamins and cell salts essential for good nutrition. Kelp powder can be used as a sodium chloride (table salt) substitute, sprinkled on foods in place of salt. It is beneficial for the nervous system, brain and the cardiovascular system. It is very important for pregnant women. If you have thyroid problems, consult with your health care provider before using. As a dietary supplement, take 1/4 teaspoon 1 to 3 times daily, preferably with meals. Use 6 to 12 drops of liquid extract-tincture in juice, water, under the tongue or as desired. May be taken 3 times daily.

  • Kelp Herbal Products
  • Lecithin
    Granules or Capsules
    Granules: 1 tablespoon 3 times daily, with meals.
    Capsules: 1,200 mg 3 times daily, with meals.
    Needed for proper brain function and healthy cell membranes. Improves memory and protects nervous system cells. Works well as an antioxidant when taken with Vitamin E. A fat emulsifier.


    Soy lecithin promotes liver cell regeneration and protects the liver from toxic damage. Soy lecithin may cause mild diarrhea when first used.

  • Lecithin Supplement Products
  • L-Glutathione
    As directed on label, on an empty stomach. Essential for the functioning of the immune system and protects the liver. Glutathione is found to be deficient in cancer growth. Inhibits the formation of free radicals. Aids in red blood cell integrity and protects immune cells. Aids in blocking damage from toxic metals and radiation.


  • Glutathione Supplement Products
  • Multi-Vitamin & Multi-Mineral Complex
    As directed on label. Basic for stabilizing vitamin and mineral imbalances in toxic conditions. Use a hypoallergenic high-potency formula.


    The vitamins and minerals in iron free Multi-Vitamin & Multi-Mineral supplements play many important roles in the body: antioxidants to protect fats, cells and DNA, coenzyme precursors for energy production and metabolism, and cofactors for hormones and enzymes which regulate body processes.

  • Multivitamin Supplement Products
  • Multimineral Supplement Products
  • Oxy-Cleanse
    As directed on label. Helps remove heavy metals, other pollutants, and anaerobic pathogens from the body.


    Oxy-Cleanse represents a revolution in colon care with a unique oxygen based process. Its multifaceted approach increases bowel activity and removes old impacted fecal matter as it detoxifies and rejuvenates the entire colon without psyllium or herbs. Initially, take 2 capsules up to 3 times daily on an empty stomach or as directed. For a complete cleanse, use 3 to 4 weeks. For daily maintenance after achieving desired results, 1 capsules up to 3 times daily on an empty stomach or as needed.

  • Oxygen-Enhancing Supplement Products
  • SAM-e
    (S-Adenosylmethionine)
    As directed on label. Helps reduce stress and nervousness caused by excess aluminum. Gives a sense of well-being. Caution: Do not use if you have manic-depressive disorder or take prescription antidepressants.


  • SAM-e Supplement Products
  • Vitamin B Complex
    Plus Extra
    Vitamin B-6 (Pyridoxine)
    And
    Vitamin B-12
    100 mg 3 times daily.

    50 mg 3 times daily.

    300 mcg 3 times daily.
    The B vitamins, especially B-6, are important in ridding the intestinal tract of excess metals and in removing them from the body. Sublingual forms are recommended for better absorption. Injections (under a health care provider's supervision) may be necessary.


    Vitamin B complex is important for healthy skin tones, proper digestion, for repair and replacement of lost nutrients, aids in healing.

  • Vitamin B Complex Supplement Products
  • Vitamin B-6 (Pyridoxine) Supplement Products
  • Vitamin B-12 Supplement Products
  • Vitamin E
    200 IU daily. A powerful antioxidant. Fights cellular aging by protecting cell membranes. Also improves circulation and prolongs the life of red blood cells. An antioxidant that enhances healing. Use d-alpha-tocopherol form.


  • Vitamin E Supplement Products





  • NOTIFY YOUR HEALTH CARE PROVIDER

  • If you have an aluminum toxicity or suspect aluminum toxicity and may need professional consultation and hair analysis testing for verification.
  • If you have any increase of symptoms or other signs of aluminum toxicity.
  • If you have any unexpected or unusual symptoms. Some people may have sensitivity, allergies, or other health conditions which would prevent them from using certain herbs or other treatments.






  • ALUMINUM TOXICITY PRODUCTS


    Information for help with aluminum toxicity, a serious condition that occurs when a person absorbs excessive amounts of aluminum, a poisonous metal that deposits itself in the brain.

  • Acacia Fiber Herbal Products
  • Apple Pectin Fiber Products
  • Burdock Herbal Products
  • Calcium Ascorbate Supplement Products
  • Calcium Pyruvate Supplement Products
  • Chlorella Herbal Products
  • Echinacea Herbal Products
  • Fiber Complex Supplement Products
  • Flavonoids Supplement Products
  • Garlic Herbal Products
  • Ginkgo Biloba Herbal Products

  • Ginseng Herbal Products
  • Ginseng Herbal Products
  • Glutathione Supplement Products
  • Hesperidin
  • Kelp Herbal Products
  • Lecithin Supplement Products
  • Magnesium Citramate Supplement Products
  • Malate Supplement Products
  • Multivitamin Supplement Products
  • Quercetin Supplement Products
  • SAM-e Supplement Products


  • QUALITY PRODUCTS & SUPPLEMENTS


    FTC Advertising & Affilate Disclosure: This website has an affiliate relationship with certain merchants selling products and we recieve commissions from those sales to help support this website. Any products listed here are not listed by any rating system. We do not rate any product or post any feedback about products listed here. We leave this to the individual merchants to provide. We do not provide product prices or shopping carts since you do not order these products directly from us, but from the merchant providing the products. We only provide the link to that merchant webpage with all related product information and pricing. The products are listed here by merchant, product use, quantity size or volume, and for nutritional supplements - dosage per unit. All product descriptions are provided by the merchant or manufacturer and are not our descriptive review of the product. We do not endorse any specific product or attest to its effectiveness to treat any health condition or support nutritional requirements for any individual.


    CALCIUM ASCORBATE SUPPLEMENT PRODUCTS

    HERBSPRO PRODUCTS

    HerbsPro: Calcium Ascorbate Crystals, Source Naturals, 4 oz. (6164)
    HerbsPro: Calcium Ascorbate Crystals. Solgar, 4.4 oz.
    HerbsPro: Calcium Ascorbate Crystals, Source Naturals, 8 oz. (6165)
    HerbsPro: Calcium Ascorbate Powder, Now Foods, 8 oz. (67876)
    HerbsPro: Calcium Ascorbate Crystals. Solgar, 8.8 oz
    HerbsPro: Calcium Ascorbate Powder, Now Foods, 3 lb. (67877)
    HerbsPro: Liquid C with Calcium Ascorbate, TwinLab, 300 mg, 8 fl. oz.
    HerbsPro: Liquid C with Calcium Ascorbate, TwinLab, 300 mg, 16 fl. oz.


    KALYX PRODUCTS

    Kalyx: Ascorbate C, Twinlab, 8 oz: HF A delicious blend of Vitamin C (as calcium ascorbate) plus lemon bioflavonoids, rose hips, acerola, rutin and hesperidin.


    AMAZON PRODUCTS


    Amazon: Calcium Ascorbate 100% Pure Buffered Vitamin C Powder, Now Foods, 8 oz.



    Amazon: Calcium Ascorbate Crystalline Powder, Buffered Vitamin C, Nutribiotic, 16 oz.
    Vitamin C is an essential nutrient that cannot be produced by the body and, therefore, must be replenished daily Calcium not only serves as the principle component of skeletal tissue, but also plays a vital role in many bodily functions. Most alkaline (buffered) form of vitamin C.



    Pure Calcium Ascorbate (Vitamin C) Powder, BulkSupplements. 1 Kg (2.2 lbs)



    Amazon: Calcium Ascorbate Powder, Nutribiotic, 5 lbs.


  • Nutrition Basics: Calcium Supplement Information



  • CALCIUM PYRUVATE SUPPLEMENT PRODUCTS

    HERBSPRO PRODUCTS

    HerbsPro: Calcium Pyruvate, Natural Balance, 500 mg, 90 Caps
    Calcium Pyruvate is important for energy production at the cellular level. Fitness and wellness formula.
    HerbsPro: Calcium Pyruvate, Nutricology Allergy Research, 533 mg, 90 Caps
    Calcium pyruvate is involved in ATP production, increased protein uptake, increased glucogen storage, and cellular respiration, potentially enhancing fat loss while sparing lean body mass and increasing endurance.
    HerbsPro: Pyruvate (Calcium), Now Foods, 1000 mg, 90 Tabs
    HerbsPro: Pyruvate (Calcium) Extra Strength, Now Foods, 1000 mg, 180 Tabs


    KALYX PRODUCTS

    HerbsPro: Calcium Pyruvate, Nutricology, 530 mg, 90 VCaps: N
    Calcium pyruvate is involved in ATP production, increased protein uptake, increased glucogen storage, and cellular respiration, potentially helping the body utilize fat for energy, spare lean body mass and increase endurance during exercise.


    AMAZON PRODUCTS



  • Calcium Supplement Information



  • MAGNESIUM ASCORBATE SUPPLEMENT PRODUCTS

    HERBSPRO PRODUCTS

    HerbsPro: Magnesium Ascorbate, Source Naturals, 4 oz.
    HerbsPro: Magnesium Ascorbate Crystals, Immune System Support, Source Naturals, 8 oz. (1877)
    Magnesium Ascorbate is non-acidic (pH neutral) and gentle on the digestive system. Vitamin C plays a vital role in collagen formation, amino acid metabolism, hormone synthesis, and the body's immune system. Magnesium is an essential mineral, playing a key role in over 300 enzymatic reactions in metabolism. These reactions include those involved in the Krebs cycle (one of the body's main energy production processes), energy storage, the breakdown of fatty acids, protein synthesis, DNA metabolism, the relaxation of both voluntary and involuntary muscle tissue, neuro-transmitter activity, and hormone regulation. Magnesium is stored primarily in the bones, and plays a role in bone formation.
    HerbsPro: Magnesium Ascorbate Powder, Now Foods, 8 oz.
    HerbsPro: Magnesium Ascorbate, Source Naturals, 60 Tabs
    HerbsPro: Magnesium Ascorbate, Source Naturals, 120 Tabs


    KALYX PRODUCTS

    Kalyx: Magnesium Ascorbate, Nutricology, 535 mg 100 Vegetarian Capsules: N


    AMAZON PRODUCTS


    Magnesium Ascorbate Powder, Now Foods, 8 oz.



    Amazon: Magnesium Ascorbate Crystals, Source Naturals, 8 oz.



    Amazon: Magnesium Ascorbate, Nutricology, 1000 mg, 100 VCaps



    Amazon: Magnesium Ascorbate, Source Naturals, 1000 mg, 120 Count


  • Nutrition Basics: Magnesium Supplement Information



  • MAGNESIUM CITRAMATE SUPPLEMENT PRODUCTS

    AMAZON PRODUCTS


    Amazon: Magnesium CitraMate, Thorne Research, 135mg, 90 VCaps
    Amazon: Magnesium CitraMate, Thorne Research, 135 mg, 90 Caps (2 pack)


  • Nutrition Basics: Magnesium Supplement Information



  • MALATE, MAGNESIUM MALATE, MALIC ACID SUPPLEMENT PRODUCTS

    Magnesium is a mineral that is critical for energy production and metabolism, muscle contraction, nerve impulse transmission and bone mineralization. It is required cofactor for an estimated 300 enzymes. Among the reactions catalyzed by these enzymes are fatty acid synthesis, protein synthesis and glucose metabolism. Malate is an important Krebs Cycle intermediate, indicating that it is an important molecule in the production of cellular energy derived from carbohydrates. Malic Acid is a fruit acid and is the principal acid contained in apples and many other fruits and vegetables. Its ability to bond with alkaline minerals such as calcium and magnesium may help to improve the absorption of these important nutrients. It supports energy production by allowing your body to produce ATP more efficiently, which is essential for proper muscle function. Leading healthcare professionals familiar with Fibromyalgia recommend Malic Acid, combined with Magnesium, for the chronic muscle soreness and fatigue experienced by most patients with this condition. Healthcare providers have found that patients with Fibromyalgia who use a combination of Malic Acid and Magnesium reported improvements in the reduction of muscle pain and tiredness. Malic Magnesium is a specialized formula that provides nutritional support for energy metabolism and muscle function, featuring chelated magnesium, malic acid, and select B vitamins.

    HERBSPRO PRODUCTS

    HerbsPro: Malic Acid, Olympian Labs, 90 Caps (74378)
    HerbsPro: Magnesium Malate Forte, Nutricology Allergy Research Group, 62.5 mg, 120 Tabs (46044)
    A combination of malic acid with magnesium and vitamin B2 (riboflavin). All three of these nutrients are important for energy generation. Each tablet contains: Riboflavin (Vitamin B-2) 5 mg; Magnesium (60% as Magnesium Citrate and 40% as Magnesium Hydroxide) 62.5 mg; Malic acid 250 mg.
    HerbsPro: Malic Magnesium, Ethical Nutrients, 300 mg / 75 mg, 120 Tabs (111248)
    HerbsPro: Magnesium Malate, Thompson Nutritional Products, 400 mg, 120 Tabs (67173)
    HerbsPro: Magnesium Malate, Source Naturals, 625 mg, 100 Caps (31714)
    HerbsPro: Magnesium Malate, Source Naturals, 625 mg, 200 Caps (31715)
    HerbsPro: Malic Acid, Natures Life, 800 mg, 100 VCaps (90073)
    HerbsPro: Malic Acid, Natures Life, 800 mg, 250 VCaps (90357)
    HerbsPro: Magnesium Malate, Now Foods, 1000 mg, 180 Tabs (68456)
    HerbsPro: Magnesium Malate, Source Naturals, 1250 mg, 90 Tabs (7083)
    HerbsPro: Magnesium Malate, Source Naturals, 1250 mg, 180 Caps (7084)
    HerbsPro: Magnesium Malate, Source Naturals, 1250 mg, 360 Tabs (7085)
    Source Naturals Magnesium malate is a compound of magnesium and malic acid in a dietary supplement. Malic acid is a natural fruit acid that is present in most cells in the body. Magnesium is an essential mineral. This formula is suitable for vegetarians. Ingredients include Magnesium (as magnesium malate), Malic acid (as magnesium malate and malic acid).
    HerbsPro: Magnesium Malate, Natures Life, 1300 mg, 100 Tabs (90470)
    HerbsPro: Magnesium Malate, Natures Life, 1300 mg, 250 Tabs (90537)


    KALYX PRODUCTS

    Kalyx: Magnesium Malate, Thompson Nutritional, 400 mg, 120 Tabs


    AMAZON PRODUCTS

    Amazon: Magnesium Malate Supplement Products

  • Nutrition Basics: Magnesium Supplement Information






  • MoonDragon's Womens Health Index

    | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |






    Health & Wellness Index





    AROMATHERAPY: ESSENTIAL OILS DESCRIPTIONS & USES


    Allspice Leaf Oil
    Angelica Oil
    Anise Oil
    Baobab Oil
    Basil Oil
    Bay Laurel Oil
    Bay Oil
    Benzoin Oil
    Bergamot Oil
    Black Pepper Oil
    Chamomile (German) Oil
    Cajuput Oil
    Calamus Oil
    Camphor (White) Oil
    Caraway Oil
    Cardamom Oil
    Carrot Seed Oil
    Catnip Oil
    Cedarwood Oil
    Chamomile Oil
    Cinnamon Oil
    Citronella Oil
    Clary-Sage Oil
    Clove Oil
    Coriander Oil
    Cypress Oil
    Dill Oil
    Eucalyptus Oil
    Fennel Oil
    Fir Needle Oil
    Frankincense Oil
    Geranium Oil
    German Chamomile Oil
    Ginger Oil
    Grapefruit Oil
    Helichrysum Oil
    Hyssop Oil
    Iris-Root Oil
    Jasmine Oil
    Juniper Oil
    Labdanum Oil
    Lavender Oil
    Lemon-Balm Oil
    Lemongrass Oil
    Lemon Oil
    Lime Oil
    Longleaf-Pine Oil
    Mandarin Oil
    Marjoram Oil
    Mimosa Oil
    Myrrh Oil
    Myrtle Oil
    Neroli Oil
    Niaouli Oil
    Nutmeg Oil
    Orange Oil
    Oregano Oil
    Palmarosa Oil
    Patchouli Oil
    Peppermint Oil
    Peru-Balsam Oil
    Petitgrain Oil
    Pine-Long Leaf Oil
    Pine-Needle Oil
    Pine-Swiss Oil
    Rosemary Oil
    Rose Oil
    Rosewood Oil
    Sage Oil
    Sandalwood Oil
    Savory Oil
    Spearmint Oil
    Spikenard Oil
    Swiss-Pine Oil
    Tangerine Oil
    Tea-Tree Oil
    Thyme Oil
    Vanilla Oil
    Verbena Oil
    Vetiver Oil
    Violet Oil
    White-Camphor Oil
    Yarrow Oil
    Ylang-Ylang Oil
    Aromatherapy
    Healing Baths For Colds
    Aromatherapy
    Herbal Cleansers
    Using Essential Oils


    AROMATHERAPY: HERBAL & CARRIER OILS DESCRIPTIONS & USES


    Almond, Sweet Oil
    Apricot Kernel Oil
    Argan Oil
    Arnica Oil
    Avocado Oil
    Baobab Oil
    Black Cumin Oil
    Black Currant Oil
    Black Seed Oil
    Borage Seed Oil
    Calendula Oil
    Camelina Oil
    Castor Oil
    Coconut Oil
    Comfrey Oil
    Evening Primrose Oil
    Flaxseed Oil
    Grapeseed Oil
    Hazelnut Oil
    Hemp Seed Oil
    Jojoba Oil
    Kukui Nut Oil
    Macadamia Nut Oil
    Meadowfoam Seed Oil
    Mullein Oil
    Neem Oil
    Olive Oil
    Palm Oil
    Plantain Oil
    Plum Kernel Oil
    Poke Root Oil
    Pomegranate Seed Oil
    Pumpkin Seed Oil
    Rosehip Seed Oil
    Safflower Oil
    Sea Buckthorn Oil
    Sesame Seed Oil
    Shea Nut Oil
    Soybean Oil
    St. Johns Wort Oil
    Sunflower Oil
    Tamanu Oil
    Vitamin E Oil
    Wheat Germ Oil





    HELPFUL RELATED MOONDRAGON NUTRITION BASICS LINKS

  • MoonDragon's Nutrition Basics Index
  • MoonDragon's Nutrition Basics: Amino Acids Index
  • MoonDragon's Nutrition Basics: Antioxidants Index
  • MoonDragon's Nutrition Basics: Enzymes Information
  • MoonDragon's Nutrition Basics: Herbs Index
  • MoonDragon's Nutrition Basics: Homeopathics Index
  • MoonDragon's Nutrition Basics: Hydrosols Index
  • MoonDragon's Nutrition Basics: Minerals Index
  • MoonDragon's Nutrition Basics: Mineral Introduction
  • MoonDragon's Nutrition Basics: Dietary & Cosmetic Supplements Index
  • MoonDragon's Nutrition Basics: Dietary Supplements Introduction
  • MoonDragon's Nutrition Basics: Specialty Supplements
  • MoonDragon's Nutrition Basics: Vitamins Index
  • MoonDragon's Nutrition Basics: Vitamins Introduction


  • NUTRITION BASICS ARTICLES

  • MoonDragon's Nutrition Basics: 4 Basic Nutrients
  • MoonDragon's Nutrition Basics: Avoid Foods That Contain Additives & Artificial Ingredients
  • MoonDragon's Nutrition Basics: Is Aspartame A Safe Sugar Substitute?
  • MoonDragon's Nutrition Basics: Guidelines For Selecting & Preparing Foods
  • MoonDragon's Nutrition Basics: Foods That Destroy
  • MoonDragon's Nutrition Basics: Foods That Heal
  • MoonDragon's Nutrition Basics: The Micronutrients: Vitamins & Minerals
  • MoonDragon's Nutrition Basics: Avoid Overcooking Your Foods
  • MoonDragon's Nutrition Basics: Phytochemicals
  • MoonDragon's Nutrition Basics: Increase Your Consumption of Raw Produce
  • MoonDragon's Nutrition Basics: Limit Your Use of Salt
  • MoonDragon's Nutrition Basics: Use Proper Cooking Utensils
  • MoonDragon's Nutrition Basics: Choosing The Best Water & Types of Water





  • RELATED MOONDRAGON HEALTH LINKS & INFORMATION

  • MoonDragon's Nutrition Information Index
  • MoonDragon's Nutritional Therapy Index
  • MoonDragon's Nutritional Analysis Index
  • MoonDragon's Nutritional Diet Index
  • MoonDragon's Nutritional Recipe Index
  • MoonDragon's Nutrition Therapy: Preparing Produce for Juicing
  • MoonDragon's Nutrition Information: Food Additives Index
  • MoonDragon's Nutrition Information: Food Safety Links
  • MoonDragon's Aromatherapy Index
  • MoonDragon's Aromatherapy Articles
  • MoonDragon's Aromatherapy For Back Pain
  • MoonDragon's Aromatherapy For Labor & Birth
  • MoonDragon's Aromatherapy Blending Chart
  • MoonDragon's Aromatherapy Essential Oil Details
  • MoonDragon's Aromatherapy Links
  • MoonDragon's Aromatherapy For Miscarriage
  • MoonDragon's Aromatherapy For Post Partum
  • MoonDragon's Aromatherapy For Childbearing
  • MoonDragon's Aromatherapy For Problems in Pregnancy & Birthing
  • MoonDragon's Aromatherapy Chart of Essential Oils #1
  • MoonDragon's Aromatherapy Chart of Essential Oils #2
  • MoonDragon's Aromatherapy Tips
  • MoonDragon's Aromatherapy Uses
  • MoonDragon's Alternative Health Index
  • MoonDragon's Alternative Health Information Overview
  • MoonDragon's Alternative Health Therapy Index
  • MoonDragon's Alternative Health: Touch & Movement Therapies Index
  • MoonDragon's Alternative Health Therapy: Touch & Movement: Aromatherapy
  • MoonDragon's Alternative Therapy: Touch & Movement - Massage Therapy
  • MoonDragon's Alternative Health: Therapeutic Massage
  • MoonDragon's Holistic Health Links Page 1
  • MoonDragon's Holistic Health Links Page 2
  • MoonDragon's Health & Wellness: Nutrition Basics Index
  • MoonDragon's Health & Wellness: Therapy Index
  • MoonDragon's Health & Wellness: Massage Therapy
  • MoonDragon's Health & Wellness: Hydrotherapy
  • MoonDragon's Health & Wellness: Pain Control Therapy
  • MoonDragon's Health & Wellness: Relaxation Therapy
  • MoonDragon's Health & Wellness: Steam Inhalation Therapy
  • MoonDragon's Health & Wellness: Therapy - Herbal Oils Index







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    MOONDRAGON'S REALM - WEBSITE DIRECTORY


    A website map to help you find what you are looking for on MoonDragon.org's Website. Available pages have been listed under appropriate directory headings.




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