WHAT IS ADDISON'S DISEASE?

Addison's disease is a severe or total deficiency of the hormones made in the adrenal cortex, caused by a destruction of the adrenal cortex. There are normally two adrenal glands, located above each kidney. The adrenal glands are really two endocrine (ductless or hormone producing) glands in one. The inner part of the adrenal (called the medulla) produces epinephrine (also called adrenaline ) which is produced at times of stress and helps the body respond to "fight or flight" situations by raising the pulse rate, adjusting blood flow, and raising blood sugar. However, the absence of the adrenal medulla and epinephrine does not cause disease.

In contrast, the outer portion of the adrenal, the cortex, is more critical. The adrenal cortex makes two important steroid hormones, cortisol and aldosterone. Cortisol mobilizes nutrients, modifies the body's response to inflammation, stimulates the liver to raise the blood sugar, and also helps to control the amount of water in the body. Aldosterone regulates salt and water levels which affects blood volume and blood pressure. Cortisol production is regulated by another hormone, adrenocorticotrophic hormone (ACTH), made in the pituitary gland which is located just below the brain. Classical Addison's disease results from a loss of both cortisol and aldosterone secretion due to the near total or total destruction of both adrenal glands. This condition is also called primary adrenal insufficiency. If ACTH is deficient, there will not be enough cortisol produced, although aldosterone may remain adequate. This is secondary adrenal insufficiency, which is distinctly different, but similar to Addison's disease, since both include a loss of cortisol secretion.

WHAT CAUSES ADDISON'S DISEASE?

When Dr. Thomas Addison's' first described this disease in London in 1855, the most common cause was tuberculosis. This remained the leading cause until the middle of the twentieth century when antibiotics progressively reduced TB's incidence. Since then, the major cause of Addison's disease results from an auto-immune reaction in which the body's immune system erroneously makes antibodies against the cells of the adrenal cortex and slowly destroys them. That process takes months to years. There are also several less common causes of Addison's disease: other chronic infections besides tuberculosis, especially certain fungal infections, invasion of the adrenal by cancer cells that have spread from another part of the body, especially the breast; CMV virus in association with AIDS; rarely, hemorrhage into the adrenals during shock; and the surgical removal of both adrenals.

WHY IS IT CONSIDERED A RARE DISORDER?

There are no accurate statistics on the incidence of Addison's disease in the United States. A study in London showed thirty-nine cases per million population as of 1960. Twelve were due to tuberculosis. In the non-tuberculosis group, women were three times more likely to have Addison's disease. Extrapolation of these figures to the U.S. would give about 8,800 cases, but this is probably an underestimation.

WHAT ARE THE SYMPTOMS OF ADDISON'S DISEASE?

The slowly progressive loss of cortisol and aldosterone secretion usually produces a chronic, steadily worsening fatigue, a loss of appetite, and some weight loss. Blood pressure is low and falls further when a person is standing, producing lightheadedness. Nausea, sometimes with vomiting, and diarrhea are common. The muscles are weak and often go into spasm. There are often emotional changes, particularly irritability and depression. Because of salt loss, a craving for salty foods is common. Finally, the increase in ACTH due to the loss of cortisol will usually produce a darkening of the skin that may look like an inappropriate tan on a person who feels very sick. Unfortunately, the slowly progressive chronic symptoms are usually missed or ignored until a sudden event like a flu virus, an accident, or the need for surgery suddenly precipitates a dramatic change for the worse because of the deficient response from the adrenals to one of these stresses. This is referred to as an Addisonian crisis and is a medical emergency.

HOW IS ADDISON'S DISEASE DIAGNOSES?

A medical history of the symptoms mentioned above, especially hyperpigmentation of the skin or gums, is often enough to raise a strong suspicion, prompting the appropriate tests. Quite often, however, the first clue is from the abnormal results of routine tests done in a hospital or doctor's office. These may include an elevated blood level of potassium, a low blood level of sodium, a shift in the ratio of certain white blood cells, or surprising changes on an EKG or chest x-ray that are caused by high potassium or low blood volume. Other causes for these changes, particularly from medications, must be considered first. A definitive diagnosis of Addison's disease requires that definitive tests be carried out. These tests measure the amount of cortisol and aldosterone in the blood and urine, and document a lack of the normal increase in the levels of these two hormones after administration of ACTH given by injection. An elevated blood level of ACTH should also be found. If the patient is very sick and Addison's disease is suspected, treatment can be initiated while the diagnostic tests are being done. Once the diagnosis of Addison's disease is established, an effort should be made to find the cause by checking for tuberculosis and other infections through skin tests and x-rays.

HOW IS ADDISON'S DISEASE TREATED?

Since all of the manifestations of Addison's disease are caused by the lack of cortisol and aldosterone, the treatment is to replace these with similar steroids. Cortisol is usually replaced orally by cortisone acetate or hydrocortisone tablets divided into morning and afternoon doses. Aldosterone is replaced by an aldosterone-like synthetic steroid, fludrocortisone (Florinef) tablets given once daily. The doses of each of these medications are adjusted for the individual's size and any co-existing medical conditions. In emergencies or during surgery, hydrocortisone must be given intravenously. Patients with Addison's disease should be taught to treat minor illnesses with extra salt and fluids. This is especially important if fever, vomiting or diarrhea is present. Persistence of these signs requires immediate treatment in an emergency room with intravenous saline (salt water) and hydrocortisone. Since Addison's disease is a chronic condition, daily replacement medication can never be stopped.

Proper maintenance treatment requires regular visits to a physician for examinations, laboratory tests, and discussions about symptoms. Certain blood tests, including sodium, potassium, blood counts and plasma renin are very useful in monitoring the response to adjustments in dosage. There is no single blood or urine test that is perfect by itself.

WHY SHOULD ADDISONIANS CONSULT AN ENDOCRINOLOGIST?

Endocrinologists are specialists in hormonal diseases, including Addison's disease. Because of the rarity of the disease, an endocrinologist will have more training and experience in properly diagnosing and treating Addison's disease than most physicians.

ARE THERE RELATED DISEASES?

Secondary adrenal insufficiency, caused by a lack of ACTH, results in a deficiency of cortisol, but usually not aldosterone. The cause is either pituitary disease, such as a tumor, or the prolonged use of "steroid" medication that suppresses ACTH. The treatment is simply to replace cortisol, usually with the synthetic steroid prednisone, but sometimes hydrocortisone or cortisone acetate.

Auto-immune Addison's disease, the most common type, can be associated with other auto-immune diseases that similarly affect other endocrine glands. The most common one is the thyroid. If an underactive thyroid (hypothyroidism) coexists with Addison's disease, this is called Schmidt's syndrome. Less commonly associated auto-immune diseases are insulin-dependent diabetes mellitus, and insufficiencies of the parathyroid glands, gonads, and vitamin B-12 absorption (pernicious anemia).

HOW NORMAL IS AN ADDISONIAN'S LIFE?

As long as the proper dose of replacement medication is taken every day, an Addisonian can have a normal crisis-free life. There are no specific physical or occupational restrictions. Routine care includes regular physician visits, avoidance of dehydration, and the use of extra medication during illness. Pregnancy is possible, but will require extra monitoring of the replacement medication. Every Addisonian should wear an identification bracelet or necklace stating that he or she has the disease, to insure proper emergency treatment. An identification card outlining treatment is also suggested. Today, people with Addison's disease should have a normal life expectancy.

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ADDISON'S DISEASE SUPPLEMENTS

Addison's Disease Supplements: Information for help with Addison's disease, a rare disorder that occurs when the adrenal glands are not able to produce enough of the hormones cortisol and aldosterone.

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ASTRAGALUS PRODUCTS Astragalus helps maintain normal functions of the liver, lung, kidney, stomach and heart, to boost energy, defer aging, detoxify, etc. To bolster white blood cells growth, support the immune systems, and to promote the effect of other herbs, and help reduce side effect of chemotherapy and radiation. Astragalus root is used to stimulate the immune system and astragalus root improves adrenal gland function and digestion. Astragalus root is considered to have a normalizing effect on the body's functions. Astragalus is an important herb and the chief energy tonic in Asian medicine and is commonly included in Chinese cuisine. Early Chinese writings refer to Astragalus as The Superior Tonic. Traditional Chinese medicine prescribes astragalus for maladies related to deficiencies of the "spleen", the energy body responsible for digesting food and "grounding" the energies of the body in the environment. 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Proprietary Formula consisting of Astragalus Root (astragalus membranaceus) in a base of Codonopsis Root, Licorice Root, Schisandra Berry, Ligustrum Fruit, Ligusticum Wallichi Root, White Peony Root, and Reishi Mushroom. Take 2 tablets, three times daily. HerbsPro: Astragalus Root, Natures Way, 60 VCaps HerbsPro: Astragalus Root, Natures Way, 100 Caps HerbsPro: Astragalus Root, Standardized, Natures Answer, 250/250 mg, 60 VCaps HerbsPro: Astragalus Root, Natures Answer, 500 mg, 90 Caps HerbsPro: Astragalus, Now Foods, 500 mg, 100 Caps HerbsPro: Full Spectrum Astragalus Extract, Botanical Immune Support, Planetary Herbals, 500 mg, 120 Tabs House of Nutrition: Astragalus Root Extract, Alcohol-Free, Gaia Herb, 4 oz. 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COENZYME Q-10 - COQ10 PRODUCTS CoQ10 is a coenzyme for several key steps in the production of energy within each cell, and an antioxidant important in its clinical effects. It is these two properties make CoQ10 one of the best supplements available today. Kalyx: Super CoQ10, TwinLab, 50 mg, 60 Caps Kalyx: CoEnzyme Q-10, Natrol, Time Release, 100 mg, 30 VCaps Kalyx: CoEnzyme Q-10, Natrol, 200 mg, 45 Softgels Kalyx: CoEnzyme Q-10, Natrol, 50 mg, 60 Caps HerbsPro: Coenzyme Q10, Vegan, 25 mg, 60 Tabs HerbsPro: Coenzyme Q10 Sublingual, Peppermint, Source Naturals, 30 mg, 120 Tabs HerbsPro: Coenzyme Q10, Source Naturals, 30 mg, 120 Softgels HerbsPro: Coenzyme Q10 Sublingual, Peppermint, Source Naturals, 60 mg, 120 Tabs HerbsPro: Coenzyme Q10, Source Naturals, 75 mg, 120 Caps HerbsPro: Coenzyme Q10, Source Naturals, 100 mg, 90 Softgels HerbsPro: Coenzyme Q10, Ultra Potency, Source Naturals, 125 mg, 60 Caps HerbsPro: Coenzyme Q10, Source Naturals, 200 mg, 60 Softgels HerbsPro: Coenzyme Q10, Source Naturals, 400 mg, 60 Softgels HerbsPro: CoQ10 Clinical Strength, Healthy Origins, 300 mg, 150 Softgels HerbsPro: CoQ10, 100% Natural, Healthy Origins, 200 mg, 150 Softgels HerbsPro: CoQ10, Now Foods, 100 mg, 150 Softgels HerbsPro: CoQ10 Chewmelt, FoodScience of Vermont, 100 mg, 60 Tabs HerbsPro: CoQ10, Enzymatic Therapy, 60 mg, 60 Tabs HerbsPro: CoQ10 Liquid, Dynamic Health Labs, 50 mg, 8 fl. oz. HerbsPro: CoQ10, Enzymatic Therapy, 50 mg, 120 Softgels HerbsPro: CoQ10, Enzymatic Therapy, 30 mg, 60 Softgels TakeHerb: High Absorption CoQ10, Increases Energy, Doctors Best, 100 mg, 60 Caps TakeHerb: Super Absorbable CoQ10 With D'Limonene, Life Extension, 50 mg, 60 Softgels TakeHerb: Super Absorbable CoQ10 With D'Limonene, Life Extension, 100 mg, 100 Softgels TakeHerb: CoQ10, Natural Trans Isomer, Health Origins, 100 mg, 150 Softgels TakeHerb: CoQ10, Natural Trans Isomer, Health Origins, 300 mg, 60 Softgels TakeHerb: CoQ10, Enzymatic Therapy, 200 mg, 30 Tabs

ECHINACEA PRODUCTS Three species of the Echinacea herb are useful in medicine: Echinacea augustifolia, Echinacea purpurea, and Echinacea pallida. Research has shown that Echinacea increases production of interferon in the body, which helps increase antiviral activity against influenza (flu) and herpes, an inflammation of the skin and mouth. It is antiseptic and antimicrobial, with properties that act to increase the number of white blood cells available to destroy bacteria and slow the spread of infection. This herb is thought to be an immune stimulant. Taking this herb at the first sign of cold or flu symptoms can actually shorten the term of a cold or even abort it when caught early enough. Echinacea Root is also known as Purple Coneflower and considered very valuable by the North American Indians. Echinacea possesses confirmed anitbacterial and antiviral properties. It is profoundly supportive of the immune system, and Echinacea's therapeutic power amazed practitioners. Echinacea is effective both internally, against such as colds, flu and tonsilitis, and externally against many kinds of stubborn skin problems. The decoction can be used as a mouthwash for pyorrhoea and gingivitis, and as a douche for vaginal infections. Echinacea is the subject of much contemporary research. Its complex chemistry seems to support the immune system by activating white blood cells. Echinacea also increases the production of interferon, an important part of the body’s response to viral infections. Many double-blind studies have confirmed that echinacea is effective for treating colds and flu. Other modern clincial studies confirm that echinacea, taken both internally and used as a douche, is extremely effective against vaginal yeast infections. Echinacea is usually taken at the onset of a cold or flu and continued for 7 to 14 days. When using a powdered extract, take 300 mg 3 times a day. The standard dosage of an alcohol tincture (1:5) is 3 to 4 ml 3 times daily. 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TYROSINE PRODUCTS L-Tyrosine is used to treat insomnia, improve muscle tone, improve skin and hair pigment and depression and anxiety. L-Tyrosine should not to be used while taking prescription antidepressants or MAO inhibitors. Kalyx: L-Tyrosine, TwinLab, 500 mg, 100 Caps Kalyx: L-Tyrosine, FoodScience Labs, 500 mg, 60 VCaps HerbsPro: L-Tyrosine Powder, Amino Acid Free-Form Supplement, 100 gm, 3.53 oz. HerbsPro: Tyrosine Powder, Now Foods, 4 oz. HerbsPro: L-Tyrosine, Now Foods, 500 mg, 120 Caps HerbsPro: L-Tyrosine, Nutricology, 500 mg, 100 Caps House of Nutrition: L-Tyrosine, Douglas Lab, 800 mg, 100 Caps House of Nutrition: L-Tyrosine, Ecological Formula, 800 mg, 100 Caps TakeHerb: L-Tyrosine With Vitamin B-6, Aids Melanin Production & Helps Moon, Health Herbs, 500 mg, 60 Caps

MILK THISTLE / SILYMARIN PRODUCTS Milk Thistle (Silymarin) may be taken in capsule form and prevents and treats cirrhosis and other liver disorders. Milk thistle extract is a potent antioxidant which prevents harm from free radicals and lends nutritional support to the liver. Milk thistle seed extract contains silymarin, a unique type of flavonoid-like compound considered the active ingredient of milk thistle. Take 600 mg (about 5 tablets) daily. Note: Milk thistle may cause mild diarrhea. If this occurs, reduce the dosage or discontinue use. Milk Thistle (standardized to 80 mg silymarin) is taken consistently before pregnancy and during the first trimester will help the liver to gently detox and help hyperemesis to be avoided. Clinical studies using standardized milk thistle extract show that it supports and promotes normal liver function. The active bioflavonoid complex, silymarin, is a powerful antioxidant that exerts a protective effect against substances harmful to the liver. Thisilyn is especially recommended for those who use alcohol, smoke or are exposed to environmental pollutants. Thisily, the unique standardized milk thistle extract, is the world's standard for quality. The milk thistle used to manufacture Thisilyn is carefully extracted and tested for purity, ensuring all the plant's desirable benefits remain bioavailable. Mountain Rose Herbs: Milk Thistle, Organic Bulk Herbs Starwest Botanicals: Milk Thistle, Whole Seed, Organic, 1 lb. Starwest Botanicals: Milk Thistle, Whole Seed, 1 lb. Starwest Botanicals: Milk Thistle Leaf, Cut & Sifted, Organic, 1 lb. Starwest Botanicals: Milk Thistle Seed Powder, 1 lb. Starwest Botanicals: Milk Thistle Seed Powder, Organic, 1 lb. Starwest Botanicals: Milk Thistle Standardized Extract (Silybum marianum). 80% Silymarin, 1 lb. Starwest Botanicals: Milk Thistle Extract, Organic, 1 fl. oz. Starwest Botanicals: Milk Thistle Extract, Organic, 4 fl. oz. Starwest Botanicals: Milk Thistle Herb, Standardized Extract Capsules, 80% Silymarin, 150 mg, 100 Caps Starwest Botanicals: Milk Thistle Herb, Standardized Extract Caps, 80% Silymarin, 150 mg, 500 Caps Kalyx: Milk Thistle Advantage, Liver Support Formula, Natrol, 525 mg, 60 VCaps Kalyx: Milk Thistle, Standardized 80% Silymarin, Natures Way, 175 mg, 60 Caps Kalyx: Milk Thistle 4:1, Herbal Extracts Plus, 600 mg, 90 VCaps Kalyx: Milk Thistle, Standardized 80% Silymarin, Starwest Botanicals, 150 mg, 60 VCaps Kalyx: Milk Thistle Extract, Herb Pharm, 4 fl. oz. HerbsPro: Milk Thistle, Eclectic Institute, 600 mg, 120 Caps HerbsPro: Milk Thistle Tea, Alvita Teas, 24 Bags HerbsPro: Thisilyn Milk Thistle Extract, Natures Way, 175 mg, 100 Caps HerbsPro: Milk Thistle, Organic, Genceutic Naturals, 350 mg, 60 Caps HerbsPro: Milk Thistle Complex, Liver Gallbladder Drops, Bioforce USA, 1.7 fl. oz. HerbsPro: Milk Thistle, Alcohol Free, Natures Answer, 1 fl. oz. HerbsPro: Milk Thistle Extract, Eclectic Institute, 1 fl. oz. HerbsPro: Milk Thistle-Dandelion Extract, Eclectic Institute, 2 fl. oz. HerbsPro: Milk Thistle Extract, Eclectic Institute, 2 fl. oz. HerbsPro: Milk Thistle Extract, Herb Pharm, 4 fl. oz. House of Nutrition: Super Milk Thistle, Enzymatic, 120 Softgels TakeHerb: Milk Thistle Seed Powder, Starwest Botanicals, 1 lb. TakeHerb: Milk Thistle Seed, Protect & Regenerate Liver Cells, Health Herbs, 2 fl. oz. TakeHerb: Milk Thistle, Standardized, Promotes Healthy Liver Function, Good'n Natural, 175 mg, 100 Caps

VITAMIN B-5 - PANTOTHINE - PANTOTHENIC ACID PRODUCTS Pantothenic Acid (Vitamin B-5; Pantethine) is converted to coenzyme A, which is involved in the biochemical cycles responsible for conversion of fats, proteins and carbohydrates into energy. Needed to counteract stress. the most potent anti-stress vitamin. Kalyx: Pantethine, Nutricology, 330 mg, 60 Caps HerbsPro: Pantethine, Now Foods, 300 mg, 60 Softgels HerbsPro: Pantethine (Pantothenic Acid; Vitamin B-5), Source Naturals, 300 mg, 90 Tabs HerbsPro: Pantethine, Jarrow Formulas, 450 mg, 60 Softgels HerbsPro: Pantethine (Pantesin), Nutricology, 330 mg (600 mg), 60 VCaps HerbsPro: Pantethine, Now Foods, 600 mg, 60 Softgels HerbsPro: Pantethine Co-B-5 Sublingual, Coenzyme B-5 Precursor, Source Naturals, 25 mg, 60 Tabs House of Nutrition: Pantethine, Pure Encap, 250 mg, 60 VCaps House of Nutrition: Pantethine (Vitamin B-5; Pantothenic Acid), Cardiovasular, 165 mg (300 mg; 135 mg), 60 Tabs House of Nutrition: Pantethine, Douglas Labs, 500 mg, 50 Tabs TakeHerb: Pantethine Sublingual, Source Naturals, 25 mg, 60 Tabs TakeHerb: Pantothenic Acid (Vitamin B-5), Source Naturals, 100 mg, 250 Tabs TakeHerb: Pantothenic Acid (Vitamin B-5), Source Naturals, 250 mg, 250 Tabs TakeHerb: Pantethine (Vitamin B-5), Now Foods, 300 mg, 60 Softgels TakeHerb: Pantothenic Acid (Vitamin B-5), Source Naturals, 500 mg, 200 Tabs TakeHerb: Pantothenic Acid (Vitamin B-5), Solgar, 550 mg, 100 VCaps

SIBERIAN ELEUTHERO GINSENG PRODUCTS Siberian Ginseng, also known s Eleuthero helps bronchial disorders and boosts energy. It improves physical and mental vitality. It is an adaptogenic herb, which helps t he body to adapt to daily stress and is an ideal herb supplement for those leading a demanding and hectic lifestyle. Siberian Ginseng strengthens the adrenal and reproductive glands. It enhances immune function, helps support the immune system, prevent infection, promotes lung functioning, improve memory, endurance vitality and to balance the hormone levels in male and female, and stimulates the appetite. It useful for bronchitis, circulatory problems, diabetes, infertility, lack of energy, and stress. There is some evidence that it can help ease withdrawal from cocaine, and help improve drug or alcohol induced liver dysfunction in older adults. Siberian Ginseng protects the body against the effects of radiation exposure. It is used by athletes for overall body strengthening. Siberian Ginseng is most effective in the treatment of prolonged exhaustion and debility, resulting from overwork and long-term stress. As a decoction take 35 ml of Siberian Ginseng 2 times a day for use as a general tonic. To take in tincture form, use 1/2 teaspoon with water 3 times a day. For other forms, read follow product label directions. Caution: Do not use this herb if you have hypoglycemia, high blood pressure, or a heart disorder. Mountain Rose Herbs: Eleuthero Root, Organic Bulk Herbs Kalyx: Eleuthero Root Powder (Eleutherococcus senticosus; Siberian Ginseng), Certified Organic, Frontier Chinese Herbs, 1 lb Kalyx: Eleuthero Root (Eleutherococcus senticosus; Siberian Ginseng), Cut & Sifted, Certified Organic, Frontier Chinese Herbs, 1 lb Kalyx: Eleuthero Root Extract, Starwest Botanicals, Certified Organic, 1 fl. oz. Kalyx: Eleuthero Root Extract, Health & Herbs, 2 fl. oz. Kalyx: Eleuthero Root Extract, Starwest Botanicals, Certified Organic, 4 fl. oz. Kalyx: Eleuthero Root Extract, Health & Herbs, 8 fl. oz. TakeHerb: Siberian Eleuthero Tea, Sun Chlorella Products, 25 Tea Bags TakeHerb: Eleuthero Vascutone Herb Tea, Health King, 20 Tea Bags TakeHerb: Siberian Eleuthero, Imperial Ginseng, 2500 mg, 100 Caps TakeHerb: Eleuthero, NOW Foods, 500 mg, 250 Caps TakeHerb: Eleuthero Root, Starwest Botanicals, 470 mg, 100 Caps TakeHerb: Eleuthero Root, Starwest Botanicals, 470 mg, 500 Caps TakeHerb: Siberian Eleuthero Regular, Sun Chlorella Products, 300 Tabs TakeHerb: Siberian Eleuthero, Nature's Way, 235 mg Root & 250 mg Extract, 180 Caps TakeHerb: Eleuthero Root, Organic Cut & Sifted, Starwest Botanicals, 1 lb TakeHerb: Eleuthero Root Powder, Organic, Starwest Botanicals, 1 lb TakeHerb: Siberian Eleuthero Root Extract, Nature's Answers, Alcohol-Free, 2 fl. oz. TakeHerb: Eleuthero Root Extract, Gaia Herbs, 2 fl. oz. TakeHerb: Eleuthero Root Extract, Gaia Herbs, 4 fl. oz. HerbsPro: Siberian Eleuthero, Imperial Elixir - Ginseng Company, 10 ml Extract Vials, 30 Count PANAX GINSENG PRODUCTS Red Panax Ginseng is often used to increase energy. This extract is made from 6 year old Red Ginseng roots plants which are a precious natural product growing in the Mountains of Chang Pai in northern China. Considered by traditional herbals as the king of herbs, ginseng's adaptogenic properties (how it helps and balances and restores the body and mind when dealing with stress related conditions) are prized by many. If you are nursing or pregnant, consult with your midwife or health care provider before taking ginseng. Mountain Rose Herbs: Ginseng Root (Panax), Organic Bulk Herbs HerbsPro: Panax Ginseng Tea, Alvita Teas, 24 Bags HerbsPro: Panax Ginseng, Enzymatic Therapy, 50 mg, 60 Tabs HerbsPro: Panax Ginseng, Source Naturals, 10 Grain, 648 mg, 50 Tabs HerbsPro: Panax Ginseng Extract, Chinese Imports, 1.76 fl. oz.

ST. JOHN'S WORT PRODUCTS St. John's Wort is mainly used for the treatment of mild to moderate depression. It can also be used for chronic insomnia and anxiety related to depression. St. John's Wort may also be effective in relieving seasonal affective disorder (SAD). St. John's Wort extract is usually standardized to the substance hypericin. St. John's wort contains two substances, hypericin and pseudohypericin, that inhibit retroviral infections and could be useful in the treatment of AIDS. The recommended dose of St. John's Wort is 300 mg 3 times a day of an extract standardized to contain 0.3 percent hypericin; however, a few new products on the market are standardized to hyperforin content of 2 to 3 percent, instead of hypercin, and should be taken at the same dosage. If the herb bothers you, take it with food. It can take four weeks of usage to receive the full benefits of St. John's Wort. If you are taking antidepressant drugs, MAO inhibitors, SSRIs, and tricylics, or the drugs Tramadol or Imitrex, do not use St. John's Wort at the same time. Let your system completely flush those drugs out of your system before starting with the herb. If you are using Digoxin, cyclosporine, protease, inhibitors, oral contraceptives, amitriptyline, Coumadin (warfarin), theophylline, chemotherapy drugs, olanzapine or closapine, or any critical medication, St. John's Wort may cause the drugs to be less effective. St. John's Wort may have an additive effect if you are taking medications that cause sun sensitivity such as sulfa drugs, and the anti-inflammatory medication Feldene (piroxicam), as well as Prilosec or Prevacid. Caution: Individuals with HIV have an increased risk for sunburn and should avoid this herb. This herb may increase the chance of developing sun blisters if you are out in the sun too long. If you decide to use this herb, avoid sun exposure. Use with caution during pregnancy. Mountain Rose Herbs: St. Johns Wort, Certified Organic Bulk Herbs Mountain Rose Herbs: St. John's Wort Extract, Wild Harvested Herbal Extracts Starwest Botanicals: St. John's Wort Extract, Organic, 1 fl. oz. Starwest Botanicals: St. John's Wort Extract, Organic, 4 fl. oz. Starwest Botanicals: St. John's Wort Herb Capsules, 430 mg, 100 VCaps Starwest Botanicals: St. John's Wort Herb Capsules, 430 mg, 500 VCaps Starwest Botanicals: St. John's Wort Herb, Cut & Sifted, Organic, 1 lb. Starwest Botanicals: St. John's Wort Herb, Cut & Sifted, Wildcrafted, 1 lb. Starwest Botanicals: St. John's Wort Herb Powder, Organic, 1 lb. Starwest Botanicals: St. John's Wort Herb Powder, Wildcrafted, 1 lb. Kalyx: St. John's Wort, 0.3% Extract, Starwest Botanicals, 200 mg, 500 Caps Kalyx: St. John's Wort Extract, Starwest Botanicals, Certified Organic, 4 fl. oz. Kalyx: St. John's Wort Extract, Starwest Botanicals, Certified Organic 1 fl. oz. Kalyx: St. John's Wort Oil, Trinity Brand, 1 fl. oz. HerbsPro: St. John' s Wort Extract, Alcohol-Free, Black Cherry Flavor, Eclectic Institute Inc, 2 fl. oz. HerbsPro: Mood Balance (St.John' s wort & Lemon Balm), Alcohol-Free, 2 oz. TakeHerb: St. John's Wort Herb Powder, Wildcrafted, Starwest Botanicals, 1 lb TakeHerb: St. John's Wort, Oregon's Wild Harvest, Standardized 0.3% Hypercin, 90 Caps TakeHerb: St. John's Wort, Source Naturals, 450 mg, 90 Tabs TakeHerb: St. John's Wort, Source Naturals, 450 mg, 180 Tabs TakeHerb: St. John's Wort, NOW Foods, 300 mg, 250 Caps TakeHerb: St. John's Wort, Source Naturals, 300 mg, 120 Caps TakeHerb: St. John's Wort Extract, Time Release, Source Naturals, 900 mg, 60 Tabs TakeHerb: St. John's Wort Tea, Yogi Teas, 16 Bags TakeHerb: St. John's Wort Tea, Caffeine Free, Alvita Teas, 24 Bags TakeHerb: St. John's Wort Tea, Health King, 20 Bags TakeHerb: St. John's Wort Extract, Full Spectrum, Planetary Herbals, 2 fl. oz. TakeHerb: St. John's Wort Extract, Alcohol-Free, Nature's Answer, 1 fl. oz.

VALERIAN ROOT PRODUCTS Valerian root nourishes the nervous system and has soothing properties. Valerian is a safe and natural sleeping aid. It helps soothe rattled nerves and assists the body in relieving insomnia. After numerous scientific studies, Germany's Commission E approved Valerian root as a sleep aid. Mountain Rose Herbs: Valerian Root, Bulk Organic Herbs Kalyx: Valerian Plus Herbal Tea, Dr. Stuarts, 15 Tea Bags Kalyx: Valerian Extract, Standardized, Natures Way, 400 mg, 90 VCaps Kalyx: Valerian Root, Natures Way, 530 mg, 100 VCaps Kalyx: Valerian Root, Cut & Sifted, Certified Organic (Valeriana officinalis), Starwest Botanicals, 1 lb. Kalyx: Valerian Root, Cut & Sifted, Certified Organic, Frontier Bulk Herbs, 1 lb. Kalyx: Valerian Root Powder, Certified Organic, Starwest Botanicals, 1 lb. Kalyx: Valerian Root Powder, Certified Organic, Frontier Bulk Herbs, 1 lb. Kalyx: Valerian Root Extract, Certified Organic, Starwest Botanicals, 1 fl. oz. Kalyx: Valerian Root Extract, Certified Organic, Starwest Botanicals, 4 fl. oz. HerbsPro: Valerian Root Tea, Alvita Teas, 24 Bags HerbsPro: Valerian Mint Tea, Alvita Teas, 24 Bags HerbsPro: Valerian Extract, Alcohol Free, Eclectic Institute, 1 fl. oz. HerbsPro: Valerian Extract, Eclectic Institute, 2 fl. oz. HerbsPro: Valerian Extract, Herb Pharm, 4 fl. oz. HerbsPro: Valerian Glycerite Extract, Alcohol Free, Herb Pharm, 4 fl. oz. HerbsPro: Valerian Root, Now Foods, 500 mg, 250 Caps House of Nutrition: Valerian Extract, Wise Woman Herbal, 8 fl. oz.

VITAMIN C & BIOFLAVONOID PRODUCTS Vitamin C provides antioxidant protection for many of the body's' important enzyme systems. White blood cells utilize Vitamin C to help produce cytotoxic enzymes which they use to eliminate foreign matter. Kalyx: Vitamin C (Ascorbic Acid) Powder, Pure, Nutricology, 1000 mg, 120 Grams Kalyx: Vitamin C, Pure, Nutricology, 1000 mg, 100 Caps Kalyx: HerbaLozenges Orange C, Zand, 125 mg, 15 Per Bag Kalyx: Gummy Vitamin C Slices, Rainbow Light, 30 Single Serve Packets Kalyx: Fruit Snacks, 100% Vitamin C, Farley's & Sathers Candy Co., 5 lbs. Kalyx: Ester- C Powder With Citrus Bioflavonoids, American Health, 8 oz. Kalyx: Ester-C Liquid, American Health, 8 fl. oz. Kalyx: Ester-C Advanced Antioxidant Formula, American Health, 90 Vegetarian Tabs Kalyx: Ester-C Chewable Wafers, American Health, 250 mg, 125 Wafers HerbsPro: Maxi-C Complex Vitamin C, Country Life, 1000 mg, 180 Tabs TakeHerb: Ascorbic Acid Powder (Vitamin C), NOW Foods, 3 lbs. TakeHerb: Ascorbate C Powder, TwinLab, 2000 mg, 8 oz. TakeHerb: Liquid C With Rose Hips, Good'n Natural, 300 mg, 4 oz. TakeHerb: Alive! Organic Vitamin C Powder, Made With Organic Fruit, Nature's Way, 120 grams TakeHerb: Vitamin C-500 Complex With Bioflavonoids, Acerola & RoseHips, NOW Foods, 100 Tabs BIOFLAVONOID PRODUCTS Bioflavonoids are not true vitamins in the strictest sense, sometimes being referred to as vitamin P, and may be found in herbal plants, fruits, nuts and bark; and because they cannot be manufactured by the body, they must be supplied through the diet. The letter ''P'' represents permeability factor, and it was given to this group of nutrients because they improve capillary strength and permeability. Citrus Bioflavonoids are a class of flavonoids that includes Rutin, Hesperidin, Quercitin, Eriodictyl and Citron, and they are essential for the absorption of vitamin C, which should be taken simultaneously, so they may act synergistically for maximum benefit. Citrus fruits are well known for providing ample amounts of vitamin C, but they also provide Citrus Bioflavonoids, which are located in the white material just beneath the peel of citrus fruits and may be found in grapefruits, lemons, tangerines, limes and oranges. Other sources of bioflavonoids include apricots, nuts, peppers, buckwheat, blackberries, black currants cherries, grapes, plums, prunes and rose hips. In addition, several herbs also provide bioflavonoids, including Chervil, Elderberry, Hawthorne Berry, Horsetail and Shepherd's Purse. Kalyx: Citrus Bioflavonoids Powder, Herbal Extracts Plus, 1 lb. Bottle Citrus Bioflavonoids Powder - Approximately 600 mg. each capsule. 1/2 teaspoon of powder is about equal to one capsule. Powder can be consumed by sprinkling it over your food or mixing it with a syrup such as maple or chocolate. You could also mix it with orange juice. The citric acid in the orange juice will help to mask any unpleasant powder tastes. Sources: Lemon (Citrus limon) and Grapefruit (Citrus paradisi). Kalyx: Citrus Bioflavonoids, Country Life, 1000 mg, 250 Tabs Provides a unique citrus bioflavonoid complex from lemons, oranges and grapefruits. Includes Rutin. Certified Vegan. HerbsPro: Citrus Bioflavonoids Fluid Complex, Organic With Rosehips, Natures Answer, 5000 mg / Teaspoon, 8 fl oz. HerbsPro: Bioflavonoids Complex, FoodScience of Vermont, 1000 mg, 60 Tabs House of Nutrition: Bioflavonoids Complex, FoodScience of Vermont, 1000 mg, 60 Tabs A bioflavonoid complex supplement with Hesperidin, Rutin, and Bromelain. Bioflavonoids enhance the effectiveness of Vitamin C. Bioflavonoids support capillary strength and proper vascular function. House of Nutrition: Bioflavonoids Complex, Carlson Labs, 500 mg, 100 Tabs Each tablet contains 500 mg of Citrus Bioflavonoids Complelx providing not less than 250 mg of Bioflavonoids, in a base of Rose Hips. House of Nutrition: Quercetin Bioflavonoids, Allergy Research, 100 Caps Quercetin and other bioflavonoids extracted from lemon have made up the classical bioflavonoid nutritional supplements. By strengthening the outer cell membrane, these flavonoids may help stabilize cell surfaces. Contains 400 mg Lemon Bioflavonoids, 50 mg Quercetin, 50 mg Hesperidin, 50 mg Rutin, and 10 mg Ascorbyl Palmitate. Take 1 or 2 Caps 1 to 3 times daily with meals or as directed by healthcare provider. TakeHerb: Bioflavonoid Complex, Source Naturals, 60 Tabs TakeHerb: Citrus Bioflavonoid Complex, Now Foods, 700 mg, 100 Caps These Citrus Bioflavonoid Caps contain 40% total bioflavonoids. There are many varieties of bioflavonoids available and ours includes a number of flavonols, flavones, and flavanones including: Hesperidin, Eriocitrin, Naringen, Naringenin, and Quercitin. As a dietary supplement, take 2 capsules daily, preferably with meals. TakeHerb: C-Plus Citrus Bioflavonoid With Rutin, TwinLab, 1000 mg / 650 mg / 50 mg, 100 Caps TwinLab offers the highest bioflavonoid content concentrated from fresh lemons, oranges, grapefruits, limes and tangerines, along with the greatest number of individual bioflavonoids available from any manufacturer. Citrus Bioflavonoids Complex contains 50% total bioflavonoids consisting of flavanones [hesperidin, eriocitrin, naringen and naringenin], flavonols, flavones. TakeHerb: Citrus Bioflavonoid, TwinLab, 1400 mg, 100 Caps Contains the purest and highest potency source of citrus bioflavonoids available. Concentrated from fresh lemons, oranges, grapefruits, limes and tangerines. Citrus Bioflavonoids (Vitamin P) are found in whole portion of citrus fruits which may be helpful for bruising, varicose veins, spider veins, arthritis, hemorrhaging, phlebitis, cholesterol levels, herpes, cataracts, inflammation, bleeding gums, blood clots, scurvy, hemorrhoids, edema and hypertension. TakeHerb: Bioflavonoid Antioxidant Protection, Now Foods, 700 mg, 250 Caps

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